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from __future__ import division

3/4

genotype_frequencies = ['A'] * 5000 + ['B'] * 2500 + ['C'] * 1250 + ['D'] * 1250

def summarize_composition(population):
    population_size = len(population)
    print 'A: %0.4f' % (population.count('A') / population_size)
    print 'B: %0.4f' % (population.count('B') / population_size)
    print 'C: %0.4f' % (population.count('C') / population_size)
    print 'D: %0.4f' % (population.count('D') / population_size)

summarize_composition(genotype_frequencies)

from random import sample
new_genotype_frequencies = sample(genotype_frequencies,10000)
summarize_composition(new_genotype_frequencies)

new_genotype_frequencies = sample(genotype_frequencies,9000)
summarize_composition(new_genotype_frequencies)