#!/usr/bin/env python
# coding: utf-8

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import logging


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logging.basicConfig(level="DEBUG")


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from cobra.test import create_test_model


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from cobra.flux_analysis import single_gene_deletion


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model = create_test_model("textbook")


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genes = ['b0008', 'b0114', 'b2276', 'b1779']


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model.solver = "cplex"


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logging.getLogger().setLevel(logging.DEBUG)


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get_ipython().run_line_magic('time', 'single_gene_deletion(model, method="linear room", gene_list=genes, processes=1)')


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model.solver = "gurobi"


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get_ipython().run_line_magic('time', 'single_gene_deletion(model, method="linear room", gene_list=genes, processes=1)')


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model.solver = "glpk"


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model.solver.configuration.timeout = 20


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get_ipython().run_line_magic('time', 'single_gene_deletion(model, method="linear room", gene_list=genes, processes=1)')


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