For most plotting purposes the DataArray rather than the Dataset are used (see other other notebooks on how-to).
But for comparison of different items, the Dataset.plot method can be useful.
import mikeio
ds = mikeio.read("../tests/testdata/wind_north_sea.dfsu")
ds
<mikeio.Dataset> Dimensions: (6, 958) Time: 2017-10-27 00:00:00 - 2017-10-27 05:00:00 Items: 0: Wind speed <Wind speed> (meter per sec) 1: Wind direction <Wind Direction> (degree)
ds.plot.scatter(x="Wind speed", y="Wind direction");