In this notebook we will cover almost every feature, model and domain solutions provided by NLU healthcare! This is a birds eye overview and crash course of almost everything you can do with a healthcare license and NLU!
Named entities are sub-strings in a text that can be classified into catogires of a domain. For example, in the String
"Tesla is a great stock to invest in "
, the sub-string "Tesla"
is a named entity, it can be classified with the label company
by an ML algorithm.
Named entities can easily be extracted by the various pre-trained Deep Learning based NER algorithms provided by NLU.
NER models can be trained for many different domains and aquire expert domain knowledge in each of them. JSL provides a wide array of experts for various Medical, Helathcare and Clinical domains
This algorithm is provided by Spark NLP for Healthcare's MedicalNerModel
Domain | Description | Sample NLU Spells | Sample Entities | Sample Predicted Labels | Reference Links |
---|---|---|---|---|---|
ADE (Adverse Drug Events) | Find adverse drug event (ADE) related entities | med_ner.ade_biobert |
Aspirin , vomiting |
DRUG , ADE |
CADEC, Twimed |
Anatomy | Find body parts, anatomical sites a nd reference related entities | med_ner.anatomy |
tubules , nasopharyngeal aspirates , embryoid bodies , NK cells , Mitochondrial , tracheoesophageal fistulas , heart , colon cancer , cervical , central nervous system |
Tissue_structure , Organism_substance , Developing_anatomical_structure , Cell , Cellular_component , Immaterial_anatomical_entity , organ , Pathological_formation , Organism_subdivision , Anatomical_system |
AnEM |
Cellular/Molecular Biology | Find Genes, Molecules, Cell or general Biology related entities | med_ner.cellular.biobert |
human T-cell leukemia virus type 1 Tax-responsive , primary T lymphocytes , E1A-immortalized , Spi-B mRNA , zeta-globin |
DNA , Cell_type , Cell_line , RNA , Protein |
JNLPBA |
Chemical/Genes/Proteins | Find Chemical, Gene and Protein related entities | med_ner.chemprot.clinical |
nitrogen , β-amyloid , NF-kappaB |
CHEMICAL , GENE-Y , GENE-N |
ChemProt |
Chemical Compounds | Find general chemical compound related entities | med_ner.chemicals |
resveratrol , β-polyphenol |
CHEM |
Dataset by John Snow Labs |
Drug Chemicals | Find chemical and drug related entities | med_ner.drugs |
potassium , anthracyclines , taxanes |
DrugChem .DrugChem .DrugChem |
i2b2 + FDA |
Posology/Drugs | Find posology and drug related entities | med_ner.posology.biobert |
5000 units , Aspirin , 14 days , tablets , daily , topically , 30 mg |
DOSAGE , DRUG , DURATION , FORM , FREQUENCY , ROUTE , STRENGTH . |
i2b2 + FDA |
Risk Factors | Find risk factor of patient related entities | med_ner.risk_factors.biobert |
coronary artery disease , hypertension , Smokes 2 packs of cigarettes per day , morbid obesity , Actos , Works in School , diabetic , diabetic |
CAD , HYPERTENSION , SMOKER , OBESE , FAMILY_HIST , MEDICATION , PHI , HYPERLIPIDEMIA , DIABETES |
De-identification and Heart Disease Risk Factors Challenge datasets |
cancer Genetics | Find cancer and genetics related entities | med_ner.cancer |
human , Kir 3.3 , GIRK3 , potassium , GIRK , chromosome 1q21-23 , pancreas , tissues , fat andskeletal muscle , KCNJ9 , Type II , breast cancer , patients , anthracyclines , taxanes , vinorelbine , patients , breast , vinorelbine inpatients , anthracyclines |
Amino_acid , Anatomical_system , cancer , Cell , Cellular_component , Developing_anatomical_Structure , Gene_or_gene_product , Immaterial_anatomical_entity , Multi-tissue_structure , Organ , Organism , Organism_subdivision , Simple_chemical , Tissue |
CG TASK of BioNLP 2013 |
Diseases | Find disease related entities | med_ner.diseases.biobert |
the cyst , a large Prolene suture , a very small incisional hernia , the hernia cavity , omentum , the hernia , the wound lesion , The lesion , the existing scar , the cyst , the wound , this cyst down to its base , a small incisional hernia , The cyst |
Disease |
CG TASK of BioNLP 2013 |
Bacterial Species | Find bacterial species related entities | med_ner.bacterial_species |
Neisseria wadsworthii , N. bacilliformis , Spirochaeta litoralis |
SPECIES |
Dataset by John Snow Labs |
Medical Problem/Test/Treatment | Find medical problem,test and treatment related entities | med_ner.healthcare |
respiratory tract infection , Ourexpression studies , atorvastatin |
PROBLEM , TEST , TREATMENT |
i2b2 |
Clinical Admission Events | Find clinical admission event related entities | med_ner.admission_events |
2007 , 12 AM , Headache , blood sample , presented , emergency room , daily |
DATE , TIME , PROBLEM , TEST , TREATMENT , OCCURENCE , CLINICAL_DEPT , EVIDENTIAL , DURATION , FREQUENCY , ADMISSION , DISCHARGE |
Custom i2b2, enriched with Events |
Genetic Variants | Find genetic variant related entities | en.med_ner.genetic_variants |
rs1061170 , p.S45P , T13046C |
DNAMutation , ProteinMutation , SNP |
TMVAR |
PHI (Protected Healthcare Information) | Find PHI(Protected Healthcare) related entities | en.med_ner.deid |
2093-01-13 , David Hale , Hendrickson,</br> Ora , 7194334 , 01/13/93 , Oliveira , 25-year-old , 1-11-2000 , Cocke County Baptist Hospital , 0295 Keats Street. , (302) 786-5227 , Brothers Coal-Mine |
MEDICALRECORD , ORGANIZATION , DOCTOR , USERNAME , PROFESSION , HEALTHPLAN , URL , CITY , DATE , LOCATION-OTHER , STATE , PATIENT , DEVICE , COUNTRY , ZIP , PHONE , HOSPITAL , EMAIL , IDNUM , SREET , BIOID , FAX , AGE |
n2c2 i2b2-PHI |
Social Determinants / Demographic Data | Find Social Determinants and Demographic Data Related Entities | med_ner.jsl.enriched |
21-day-old , male , congestion , mom , suctioning yellow discharge , she , problems with his breathing , perioral cyanosis , retractions , mom , Tylenol , His , his , respiratory congestion , He , tired , fussy , albuterol |
Age , Diagnosis , Dosage , Drug_Name , Frequency , Gender , Lab_Name , Lab_Result , Symptom_Name |
Dataset by John Snow Labs |
General Clinical | Find General Clinical Entities | med_ner.jsl.wip.clinical.modifier |
28-year-old , female , gestational , diabetes , mellitus , eight , years , prior , type , two , diabetes , mellitus , T2DM , HTG-induced , pancreatitis , three , years , prior , acute , hepatitis , obesity , body , mass , index , BMI , kg/m2 , polyuria , polydipsia , poor , appetite , vomiting , Two , weeks , prior , she , five-day , course |
Injury_or_Poisoning , Direction , Test , Admission_Discharge , Death_Entity , Relationship_Status , Duration , Respiration , Hyperlipidemia , Birth_Entity , Age , Labour_Delivery , Family_History_Header , BMI , Temperature , Alcohol , Kidney_Disease , Oncological , Medical_History_Header , Cerebrovascular_Disease , Oxygen_Therapy , O2_Saturation , Psychological_Condition , Heart_Disease , Employment , Obesity , Disease_Syndrome_Disorder , Pregnancy , ImagingFindings , Procedure , Medical_Device , Race_Ethnicity , Section_Header , Symptom , Treatment , Substance , Route , Drug_Ingredient , Blood_Pressure , Diet , External_body_part_or_region , LDL , VS_Finding , Allergen , EKG_Findings , Imaging_Technique , Triglycerides , RelativeTime , Gender , Pulse , Social_History_Header , Substance_Quantity , Diabetes , Modifier , Internal_organ_or_component , Clinical_Dept , Form , Drug_BrandName , Strength , Fetus_NewBorn , RelativeDate , Height , Test_Result , Sexually_Active_or_Sexual_Orientation , Frequency , Time , Weight , Vaccine , Vital_Signs_Header , Communicable_Disease , Dosage , Overweight , Hypertension , HDL , Total_Cholesterol , Smoking , ` |
Dataset by John Snow Labs |
Radiology | Find Radiology related entities | med_ner.radiology.wip_clinical |
Bilateral , breast , ultrasound , ovoid mass , 0.5 x 0.5 x 0.4 , cm , anteromedial aspect , left , shoulder , mass , isoechoic echotexture , muscle , internal color flow , benign fibrous tissue , lipoma |
ImagingTest , Imaging_Technique , ImagingFindings , OtherFindings , BodyPart , Direction , Test , Symptom , Disease_Syndrome_Disorder , Medical_Device , Procedure , Measurements , Units |
Dataset by John Snow Labs, MIMIC-CXR and MT Radiology texts |
Radiology Clinical JSL-V1 | Find radiology related entities in clinical setting | med_ner.radiology.wip_greedy_biobert |
Bilateral , breast , ultrasound , ovoid mass , 0.5 x 0.5 x 0.4 , cm , anteromedial aspect , left , shoulder , mass , isoechoic echotexture , muscle , internal color flow , benign fibrous tissue , lipoma |
Test_Result , OtherFindings , BodyPart , ImagingFindings , Disease_Syndrome_Disorder , ImagingTest , Measurements , Procedure , Score , Test , Medical_Device , Direction , Symptom , Imaging_Technique , ManualFix , Units |
Dataset by John Snow Labs, |
Genes and Phenotypes | Find Genes and Phenotypes (the observable physical properties of an organism) related entities | med_ner.human_phenotype.gene_biobert |
APOC4 , polyhydramnios |
GENE , PHENOTYPE |
PGR_1, PGR_2 |
Normalized Genes and Phenotypes | Find Normalized Genes and Phenotypes (the observable physical properties of an organism) related entities | med_ner.human_phenotype.go_biobert |
protein complex oligomerization , defective platelet aggregation |
GO , HP |
PGR_1, PGR_2 |
Radiology Clinical JSL-V2 | Find radiology related entities in clinical setting | med_ner.jsl.wip.clinical.rd |
Kidney_Disease , HDL , Diet , Test , Imaging_Technique , Triglycerides , Obesity , Duration , Weight , Social_History_Header , ImagingTest , Labour_Delivery , Disease_Syndrome_Disorder , Communicable_Disease , Overweight , Units , Smoking , Score , Substance_Quantity , Form , Race_Ethnicity , Modifier , Hyperlipidemia , ImagingFindings , Psychological_Condition , OtherFindings , Cerebrovascular_Disease , Date , Test_Result , VS_Finding , Employment , Death_Entity , Gender , Oncological , Heart_Disease , Medical_Device , Total_Cholesterol , ManualFix , Time , Route , Pulse , Admission_Discharge , RelativeDate , O2_Saturation , Frequency , RelativeTime , Hypertension , Alcohol , Allergen , Fetus_NewBorn , Birth_Entity , Age , Respiration , Medical_History_Header , Oxygen_Therapy , Section_Header , LDL , Treatment , Vital_Signs_Header , Direction , BMI , Pregnancy , Sexually_Active_or_Sexual_Orientation , Symptom , Clinical_Dept , Measurements , Height , Family_History_Header , Substance , Strength , Injury_or_Poisoning , Relationship_Status , Blood_Pressure , Drug , Temperature, ,EKG_Findings , Diabetes , BodyPart , Vaccine , Procedure , Dosage |
Dataset by John Snow Labs, | |
General Medical Terms | Find general medical terms and medical entities. | med_ner.medmentions |
Qualitative_Concept , Organization , Manufactured_Object , Amino_Acid , Peptide_or_Protein , Pharmacologic_Substance , Professional_or_Occupational_Group , Cell_Component , Neoplastic_Process , Substance , Laboratory_Procedure , Nucleic_Acid_Nucleoside_or_Nucleotide , Research_Activity , Gene_or_Genome , Indicator_Reagent_or_Diagnostic_Aid , Biologic_Function , Chemical , Mammal , Molecular_Function , Quantitative_Concept , Prokaryote , Mental_or_Behavioral_Dysfunction , Injury_or_Poisoning , Body_Location_or_Region , Spatial_Concept , Nucleotide_Sequence , Tissue , Pathologic_Function , Body_Substance , Fungus , Mental_Process , Medical_Device , Plant , Health_Care_Activity , Clinical_Attribute , Genetic_Function , Food , Therapeutic_or_Preventive_Procedure , Body_Part_Organ , Organ_Component , Geographic_Area , Virus , Biomedical_or_Dental_Material , Diagnostic_Procedure , Eukaryote , Anatomical_Structure , Organism_Attribute , Molecular_Biology_Research_Technique , Organic_Chemical , Cell , Daily_or_Recreational_Activity , Population_Group , Disease_or_Syndrome , Group , Sign_or_Symptom , Body_System |
MedMentions |
Named Entities extracted by an NER model can be further classified into sub-classes or statuses, depending on the context of the sentence. See the following two examples :
headache
headache
headaches
All sentences have the entity headache
which is of class disease
.
But there is a semantic difference on what the actual status of the disease mentioned in text is. In the first and third sentence, Billy has no headache
, but in the second sentence Billy actually has a sentence
.
The Entity Assertion
Algorithms provided by JSL solve this problem. The disease
entity can be classified into ABSENT
for the first case and into PRESENT
for the second case. The third case can be classified into PRESENT IN FAMILY
.
This has immense implications for various data analytical approaches in the helathcare domain.
I.e. imagine you want you want to make a study about hearth attacks and survival rate of potential procedures. You can process all your digital patient notes with an Medical NER model and filter for documents that have the Hearth Attack
entity.
But your collected data will have wrong data entries because of the above mentioned Entity status problem. You cannot deduct that a document is talking about a patient having a hearth attack, unless you assert that the problem is actually there which is what the Resolutions algorithms do for you.
Keep in mind: This is a simplified example, entities should actually be mapped to their according Terminology (ICD-10-CM/ICD-10-PCS, etc..) to solve disambiguity problems and based on their codes all analysis should be performed
This algorithm is provided by Spark NLP for Healthcare's AssertionDLModel
Domain | Description | Spell | Predicted Entities | Examples | Reference Dataset |
---|---|---|---|---|---|
Radiology | Predict status of Radiology related entities | assert.radiology |
Confirmed , Negative , Suspected |
- Confirmed : X-Ray scan shows cancer in lung. - Negative : X-Ray scan shows no sign of cancer in lung. - Suspected :X-Ray raises suspicion of cancer in lung but does not confirm it. |
Internal Dataset by Annotated by John Snow Labs |
Healthcare/Clinical extended and Family JSL powerd | Predict status of, Healthcare/Clinical/Family related entities. Additional training with JSL Dataset | assert.jsl |
Present , Absent , Possible , Planned , Someoneelse , Past , Family , Hypotetical |
- Present : Patient diagnosed with cancer in 1999 - Absent : No sign of cancer was shown by the scans - Possible : Tests indicate patient might have cancer - Planned : CT-Scan is scheduled for 23.03.1999 - Someoneelse : The patient gave Aspirin to daugther. - Past : The patient has no more headaches since the operation - Family : The patients father has cancer . - Hypotetical :Death could be possible. |
2010 i2b2 + Data provided by JSL |
Healthcare/Clinical JSL powerd | Predict status of Healthcare/Clinical related entities. Additional training with JSL Dataset | assert.jsl_large |
present , absent , possible , planned , someoneelse , past |
- present : Patient diagnosed with cancer in 1999 - absent : No sign of cancer was shown by the scans - possible : Tests indicate patient might have cancer - planned : CT-Scan is scheduled for 23.03.1999 - someoneelse : The patient gave Aspirin to daugther - past : The patient has no more headaches since the operation |
2010 i2b2 + Data provided by JSL |
Healthcare/Clinical classic | Predict status of Healthcare/Clinical related entities | assert.biobert |
present , absent , possible , conditional , associated_with_someone_else ,hypothetical |
- present : Patient diagnosed with cancer in 1999 - absent : No sign of cancer was shown by the scans - possible : Tests indicate patient might have cancer - conditional If the test is positive, patient has AIDS - associated_with_someone_else : The patients father has cancer . - hypothetical :Death could be possible. |
2010 i2b2 |
Named entities are sub-strings in a text that can be classified into catogires of a domain. For example, in the String
"Tesla is a great stock to invest in "
, the sub-string "Tesla"
is a named entity, it can be classified with the label company
by an ML algorithm.
Named entities can easily be extracted by the various pre-trained Deep Learning based NER algorithms provided by NLU.
After extracting named entities an entity resolution algorithm can be applied to the extracted named entities. The resolution algorithm classifies each extracted entitiy into a class, which reduces dimensionality of the data and has many useful applications. For example :
The sub-strings Tesla
, TSLA
and Tesla, Inc
are all named entities, that are classified with the labeld company
by the NER algorithm. It tells us, all these 3 sub-strings are of type company
, but we cannot yet infer that these 3 strings are actually referring to literally the same company.
This exact problem is solved by the resolver algorithms, it would resolve all these 3 entities to a common name, like a company ID. This maps every reference of Tesla, regardless of how the string is represented, to the same ID.
This example can analogusly be expanded to healthcare any any other text problems. In medical documents, the same disease can be referenced in many different ways.
With NLU Healthcare you can leverage state of the art pre-trained NER models to extract Medical Named Entities (Diseases, Treatments, Posology, etc..) and resolve these to common healthcare disease codes.
This algorithm is provided by Spark NLP for Healthcare's SentenceEntitiyResolver
Domain/Terminology | Description | Sample NLU Spells | Sample Entities | Sample Predicted Codes | Reference Links |
---|---|---|---|---|---|
ICD-10 / ICD-10-CM (International Classification of Diseases - Clinical Modification) | Get ICD-10-CM codes of Medical and Clinical Entities . The ICD-10 Clinical Modification (ICD-10-CM) is a modification of the ICD-10, authorized by the World Health Organization , used as a source for diagnosis codes in the U.S. Be aware, ICD10-CM is often referred to as ICD10 |
resolve.icd10cm.augmented |
hypertension , gastritis |
I10 , K2970 |
ICD-10-CM , WHO ICD-10-CM |
ICD-10-PCS (International Classification of Diseases - Procedure Coding System) | Get ICD-10-PCS codes of Medical and Clinical Entities . The International Classification of Diseases, Procedure Coding System (ICD-10-PCS) , is a U.S. cataloging system for procedural code It is maintaining by Centers for Medicare & Medicaid Services |
resolve.icd10pcs |
hypertension , gastritis |
DWY18ZZ , 04723Z6 |
ICD10-PCS, CMS ICD-10-PCS |
ICD-O (International Classification of Diseases, Oncollogy) Topography & Morphology codes | Get ICD-0 codes of Medical and Clinical Entities . The International Classification of Diseases for Oncology (ICD-O) , is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. |
resolve.icdo.base |
metastatic lung cancer |
9050/3 +C38.3 , 8001/3 +C39.8 |
ICD-O Histology Behaviour dataset |
HCC (Hierachical Conditional Categories) | Get HCC codes of Medical and Clinical Entities . Hierarchical condition category (HCC) relies on ICD-10 coding to assign risk scores to patients. Along with demographic factors (such as age and gender), insurance companies use HCC coding to assign patients a risk adjustment factor (RAF) score. |
resolve.hcc |
hypertension , gastritis |
139 , 188 |
HCC |
ICD-10-CM + HCC Billable | Get ICD-10-CM and HCC codes of Medical and Clinical Entities . |
resolve.icd10cm.augmented_billable |
metastatic lung cancer |
C7800 + ['1', '1', '8'] |
ICD10-CM HCC |
CPT (Current Procedural Terminology) | Get CPT codes of Medical and Clinical Entities . The Current Procedural Terminology(CPT) is developed by the American Medical Association (AMA) and used to assign codes to medical procedures/services/diagonstics. The codes are used to derive the amount of payment a healthcare provider may receives from insurance companies for the provided service.receives |
resolve.cpt.procedures_measurements |
calcium score , heart surgery |
82310 , 33257 |
CPT |
LOINC (Logical Observation Identifiers Names and Codes) | Get LOINC codes of Medical and Clinical Entities . Logical Observation Identifiers Names and Codes (LOINC) developed by theU.S. organization Regenstrief Institute |
resolve.loinc |
acute hepatitis ,obesity |
28083-4 ,50227-8 |
LOINC |
HPO (Human Phenotype Ontology) | Get HPO codes of Medical and Clinical Entities . |
resolve.HPO |
cancer , bipolar disorder |
0002664 , 0007302 , 0100753 |
HPO |
UMLS (Unified Medical Language System) CUI | Get UMLS codes of Medical and Clinical Entities . |
resolve.umls.findings |
vomiting , polydipsia , hepatitis |
C1963281 , C3278316 , C1963279 |
UMLS |
SNOMED International (Systematized Nomenclature of Medicine) | Get SNOMED (INT) codes of Medical and Clinical Entities . |
resolve.snomed.findings_int |
hypertension |
148439002 |
SNOMED |
SNOMED CT (Clinical Terms) | Get SNOMED (CT) codes of Medical and Clinical Entities . |
resolve.snomed.findings |
hypertension |
73578008 |
SNOMED |
SNOMED Conditions | Get SNOMED Conditions codes of Medical and Clinical Entities . |
resolve.snomed_conditions |
schizophrenia |
58214004 |
SNOMED |
RxNorm and RxCUI (Concept Uinque Indentifier) | Get Normalized RxNorm and RxCUI codes of Medical, Clinical and Drug Entities . |
resolve.rxnorm |
50 mg of eltrombopag oral |
825427 |
[RxNorm Overview] [November 2020 RxNorm Clinical Drugs ontology graph] |
Most sentences and documents have a lof of entities
which can be extracted with NER. These entities alone already provide a lot of insight and information about your data, but there is even more information extractable...
Each entity
in a sentence always has some kind of relationship
to every other entity
in the sentence. In other words, each entity pair has a relationship ! If a sentence has N entities, there are NxN
potential binary relationships and NxNxK
for k-ary relationships
.
The RelationExtraction
Algortihms provided by JSL classify for each pair of entities what the type of relationship between is, based on some domain.
A concrete use-case example:
Lets say you want to analyze the survival rate of amputation procedures
peformed on the left hand
.
Using just NER
, we could find all documents that mention the entity amputation
, left
and hand
.
The collected data will have wrong entries, imagine the following clinical note :
left
foot
and his right
hand
were amputated`This record would be part of our analysis, if we just use NER
with the above mentioned filtering.
The RelationExtraction
Algorithms provided by JSL solves this problem. The relation.bodypart.directions
model can classify for each entity pair, wether they are related or not.
In our example, it can classify that left
and foot
are related and that right
and hand
are related. Based on these classified relationships, we can easily enhance our filters and make sure no wrong records are used for our surival rate analysis.
But what about the following sentence?
left
hand
was saved but his foot
was amputated
This would pass all the NER
and Relationship
filters defined sofar. But we can easily cover this case by using the relation.bodypart.procedures
model, which can predict wether a procedure entity was peformed on some bodypart or not. In the last example, it can predict foot
and amputated
are related, buthand
and amputated
are not in relationship, aswell as left
and amputated
(since every entity pair gets a prediction).
In conclusion, we can adjust our filters to additionaly verify that the amputation
procedure is peformed on a hand
and that this hand
is in relationship with a direction entity with the value left
.
Keep in mind: This is a simplified example, entities should actually be mapped to their according Terminology (ICD-10-CM/ICD-10-PCS, etc..) to solve disambiguity problems and based on their codes all analysis should be performed
These algorithm are provided by Spark NLP for Healthcare's RelationExtraction and RelationExtractionDL
Domain | Description | Sample NLU Spells | Predictable Relationships and Explanation |
---|---|---|---|
Dates and Clinical Entities | Predict binary temporal relationship between Date Entities and Clinical Entities |
relation.date |
- 1 for Date Entity and Clinical Entity are related. - 0 for Date Entity and Clinical Entity are not related |
Body Parts and Directions | Predict binary direction relationship between Bodypart Entities and Direction Entities |
relation.bodypart.direction |
- 1 for Body Part and Direction are related - 0 for Body Part and Direction are not related |
Body Parts and Problems | Predict binary location relationship between Bodypart Entities and Problem Entities |
relation.bodypart.problem |
- 1 for Body Part and Problem are related - 0 for Body Part and Problem are not related |
Body Parts and Procedures | Predict binary application relationship between Bodypart Entities and Procedure Entities |
relation.bodypart.procedure |
- 1 for Body Part and Test/Procedure are related - 0 for Body Part and Test/Procedure are not related |
Adverse Effects between drugs (ADE) | Predict binary effect relationship between Drugs Entities and Adverse Effects/Problem Entities |
relation.ade |
- 1 for Adverse Event Entity and Drug are related - 0 for Adverse Event Entity and Drug are not related |
Phenotype abnormalities,Genes and Diseases | Predict binary caused by relationship between Phenotype Abnormality Entities , Gene Entities and Disease Entities |
relation.humen_phenotype_gene |
- 1 for Gene Entity and Phenotype Entity are related - 0 for Gene Entity and Phenotype Entity are not related |
Temporal events | Predict multi-class temporal relationship between Time Entities and Event Entities |
relation.temporal_events |
- AFTER if Any Entity occured after Another Entity - BEFORE if Any Entity occured before Another Entity - OVERLAP if Any Entity during Another Entity |
Dates and Tests/Results | Predict multi-class temporal cause,reasoning and conclusion relationship between Date Entities , Test Entities and Result Entities |
relation.test_result_date |
- relation.test_result_date - is_finding_of for Medical Entity is found because of Test Entity - is_result_of for Medical Entity reason for doing Test Entity - is_date_of for Date Entity relates to time of Test/Result - 0 : No relationship |
Clinical Problem, Treatment and Tests | Predict multi-class cause,reasoning and effect relationship between Treatment Entities , Problem Entities and Test Entities |
relation.clinical |
- TrIP : A certain treatment has improved/cured a medical problem - TrWP : A patient's medical problem has deteriorated or worsened because of treatment - TrCP : A treatment caused a medical problem - TrAP : A treatment administered for a medical problem - TrNAP : The administration of a treatment was avoided because of a medical problem - TeRP : A test has revealed some medical problem - TeCP : A test was performed to investigate a medical problem - PIP : Two problems are related to each other |
DDI Effects of using Multiple Drugs (Drug Drug Interaction) | Predict multi-class effects, mechanisms and reasoning for DDI effects(Drug Drug Interaction) relationships between Drug Entities |
relation.drug_drug_interaction |
- DDI-advise when an advice/recommendation regarding aDrug Entity and Drug Entity is given - DDI-effect when Drug Entity and Drug Entity have an effect on the human body (pharmacodynamic mechanism). Including a clinical finding, signs or symptoms, an increased toxicity or therapeutic failure. - DDI-int when effect between Drug Entity and Drug Entity is already known and thus provides no additional information. - DDI-mechanism when Drug Entity and Drug Entity are affected by an organism (pharmacokinetic). Such as the changes in levels or concentration in a drug. Used for DDIs that are described by their PK mechanism - DDI-false when a Drug Entity and Drug Entity have no interaction mentioned in the text. |
Posology (Drugs, Dosage, Duration, Frequency,Strength) | Predict multi-class posology relationships between Drug Entities ,Dosage Entities ,Strength Entities ,Route Entities , Form Entities , Duration Entities and Frequency Entities |
relation.posology |
- DRUG-ADE if Problem Entity Adverse effect of Drug Entity - DRUG-DOSAGE if Dosage Entity refers to a Drug Entity - DRUG-DURATION if Duration Entity refers to a Drug Entity - DRUG-FORM if Mode/Form Entity refers to intake form of Drug Entity - DRUG-FREQUENCY if Frequency Entity refers to usage of Drug Entity - DRUG-REASON if Problem Entity is reason for taking Drug Entity - DRUG-ROUTE if Route Entity refer to administration method of Drug Entity - DRUG-STRENGTH if Strength Entity refers to Drug Entity |
Chemicals and Proteins | Predict Regulator, Upregulator, Downregulator, Agonist, Antagonist, Modulator, Cofactor, Substrate relationships between Chemical Entities and Protein Entities |
relation.chemprot |
- CPR:1 if One ChemProt Entity is Part of of Another ChemProt Entity - CPR:2 if One ChemProt Entity is Regulator (Direct or Indirect) of Another ChemProt Entity - CPR:3 if One ChemProt Entity is Upregulator/Activator/Indirect Upregulator of Another ChemProt Entity - CPR:4 if One ChemProt Entity is Downregulator/Inhibitor/Indirect Downregulator of Another ChemProt Entity - CPR:5 if One ChemProt Entity is Agonist of Another ChemProt Entity - CPR:6 if One ChemProt Entity is Antagonist of Another ChemProt Entity - CPR:7 if One ChemProt Entity is Modulator (Activator/Inhibitor) of Another ChemProt Entity - CPR:8 if One ChemProt Entity is Cofactor of Another ChemProt Entity - CPR:9 if One ChemProt Entity is Substrate and product of of Another ChemProt Entity - CPR:10 if One ChemProt Entity is Not Related to Another ChemProt Entity |
Domain | Sentence With Relationships | Predicted Relationships for Sample Sentence | Reference Links |
---|---|---|---|
Dates and Clinical Entities | This 73 y/o patient had CT on 1/12/95 , with cognitive decline since 8/11/94 . |
- 1 for CT and1/12/95 - 0 for cognitive decline and 1/12/95 - 1 for cognitive decline and 8/11/94 |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Directions | MRI demonstrated infarction in the upper - brain stem , left cerebellum and right basil ganglia |
- 1 for uppper and brain stem - 0 for upper and cerebellum - 1 for left and cerebellum |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Problems | Patient reported numbness in his left hand and bleeding from ear . |
- 1 for numbness and hand - 0 for numbness and ear - 1 for bleeding and ear |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Procedures | The chest was scanned with portable ultrasound and amputation was performed on foot |
- 1 for chest and portable ultrasound - 0 for chest and amputation - 1 for foot and amputation |
Internal Dataset by Annotated by John Snow Labs |
Adverse Effects between drugs (ADE) | Taking Lipitor for 15 years, experienced much sever fatigue ! Doctor moved me to voltaren 2 months ago , so far only experienced cramps |
- 1 for sever fatigue and Liptor - 0 for sever fatigue and voltaren - 0 for cramps and Liptor - 1 for cramps and voltaren |
Internal Dataset by Annotated by John Snow Labs |
Phenotype abnormalities,Genes and Diseases | She has a retinal degeneration , hearing loss and renal failure , short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive. |
- 1 for hearing loss and SH3PXD2B - 0 for retinal degeneration and hearing loss - 1 for retinal degeneration and autosomal recessive |
PGR aclAntology |
Temporal events | She is diagnosed with cancer in 1991 . Then she was admitted to Mayo Clinic in May 2000 and discharged in October 2001 |
- OVERLAP for cancer and 1991 - AFTER for additted and Mayo Clinic - BEFORE for admitted and discharged |
Temporal JSL Dataset and n2c2 |
Dates and Tests/Results | On 23 March 1995 a X-Ray applied to patient because of headache , found tumor in brain |
- is_finding_of for tumor and X-Ray - is_result_of for headache and X-Ray - is_date_of for 23 March 1995 and X-Ray |
Internal Dataset by Annotated by John Snow Labs |
Clinical Problem, Treatment and Tests | - TrIP : infection resolved with antibiotic course - TrWP : the tumor was growing despite the drain - TrCP : penicillin causes a rash - TrAP :Dexamphetamine for narcolepsy - TrNAP : Ralafen was not given because of ulcers - TeRP : an echocardiogram revealed a pericardial effusion - TeCP : chest x-ray for pneumonia - PIP : Azotemia presumed secondary to sepsis |
- TrIP for infection and antibiotic course - TrWP for tumor and drain - TrCP for penicillin andrash - TrAP for Dexamphetamine and narcolepsy - TrNAP for Ralafen and ulcers - TeRP for echocardiogram and pericardial effusion - TeCP for chest x-ray and pneumonia - PIP for Azotemia and sepsis |
2010 i2b2 relation challenge |
DDI Effects of using Multiple Drugs (Drug Drug Interaction) | - DDI-advise : UROXATRAL should not be used in combination with other alpha-blockers - DDI-effect : Chlorthalidone may potentiate the action of other antihypertensive drugs - DDI-int : The interaction of omeprazole and ketoconazole has been established - DDI-mechanism : Grepafloxacin may inhibit the metabolism of theobromine - DDI-false : Aspirin does not interact with Chlorthalidone |
- DDI-advise for UROXATRAL and alpha-blockers - DDI-effect for Chlorthalidone and antihypertensive drugs - DDI-int for omeprazole and ketoconazole - DDI-mechanism for Grepafloxacin and theobromine - DDI-false for Aspirin and Chlorthalidone |
DDI Extraction corpus |
Posology (Drugs, Dosage, Duration, Frequency,Strength) | - DRUG-ADE : had a headache after taking Paracetamol - DRUG-DOSAGE : took 0.5ML ofCelstone - DRUG-DURATION : took Aspirin daily for two weeks - DRUG-FORM : took Aspirin as tablets - DRUG-FREQUENCY : Aspirin usage is weekly - DRUG-REASON : Took Aspirin because of headache - DRUG-ROUTE : Aspirin taken orally - DRUG-STRENGTH : 2mg of Aspirin |
- DRUG-ADE for headache and Paracetamol - DRUG-DOSAGE for 0.5ML and Celstone - DRUG-DURATION for Aspirin and for two weeks - DRUG-FORM for Aspirin and tablets - DRUG-FREQUENCY for Aspirin and weekly - DRUG-REASON for Aspirin and headache - DRUG-ROUTE for Aspirin and orally - DRUG-STRENGTH for 2mg and Aspirin |
Magge, Scotch, Gonzalez-Hernandez (2018) |
Chemicals and Proteins | - CPR:1 (Part of) : The amino acid sequence of the rabbit alpha(2A)-adrenoceptor has many interesting properties. - CPR:2 (Regulator) : Triacsin inhibited ACS activity - CPR:3 (Upregulator) : Ibandronate increases the expression of the FAS gene - CPR:4 (Downregulator) : Vitamin C treatment resulted in reduced C-Rel nuclear translocation - CPR:5 (Agonist) : Reports show tricyclic antidepressants act as agnonists at distinct opioid receptors - CPR:6 (Antagonist) : GDC-0152 is a drug triggers tumor cell apoptosis by selectively antagonizing LAPs - CPR:7 (Modulator) : Hydrogen sulfide is a allosteric modulator of ATP-sensitive potassium channels - CPR:8 (Cofactor) : polyinosinic:polycytidylic acid and the IFNα/β demonstrate capability of endogenous IFN. - CPR:9 (Substrate) : ZIP9 plays an important role in the transport and toxicity of Cd(2+) cells - CPR:10 (Not Related) : Studies indicate that GSK-3β inhibition by palinurin cannot be competed out by ATP |
- CPR:1 (Part of) for amino acid and rabbit alpha(2A)-adrenoceptor - CPR:2 (Regulator) for Triacsin and ACS - CPR:3 (Upregulator) for Ibandronate and FAS gene - CPR:4 (Downregulator) for Vitamin C and C-Rel - CPR:5 (Agonist) for tricyclic antidepressants and opioid receptors - CPR:6 (Antagonist) (Antagonist) for GDC-0152 and LAPs - CPR:7 (Modulator) for Hydrogen sulfide and ATP-sensitive potassium channels - CPR:8 (Cofactor) for polyinosinic:polycytidylic acid and IFNα/β - CPR:9 (Substrate) for ZIP9 and Cd(2+) cells - CPR:10 (Not Related) for GSK-3β and ATP |
ChemProt Paper |
!wget https://setup.johnsnowlabs.com/nlu/colab.sh -O - | bash
import nlu
--2022-04-15 12:38:41-- https://setup.johnsnowlabs.com/nlu/colab.sh Resolving setup.johnsnowlabs.com (setup.johnsnowlabs.com)... 51.158.130.125 Connecting to setup.johnsnowlabs.com (setup.johnsnowlabs.com)|51.158.130.125|:443... connected. HTTP request sent, awaiting response... 302 Moved Temporarily Location: https://raw.githubusercontent.com/JohnSnowLabs/nlu/master/scripts/colab_setup.sh [following] --2022-04-15 12:38:42-- https://raw.githubusercontent.com/JohnSnowLabs/nlu/master/scripts/colab_setup.sh Resolving raw.githubusercontent.com (raw.githubusercontent.com)... 185.199.108.133, 185.199.109.133, 185.199.110.133, ... Connecting to raw.githubusercontent.com (raw.githubusercontent.com)|185.199.108.133|:443... connected. HTTP request sent, awaiting response... 200 OK Length: 1665 (1.6K) [text/plain] Saving to: ‘STDOUT’ - 0%[ ] 0 --.-KB/s Installing NLU 3.4.3rc2 with PySpark 3.0.3 and Spark NLP 3.4.2 for Google Colab ... - 100%[===================>] 1.63K --.-KB/s in 0.001s 2022-04-15 12:38:42 (2.64 MB/s) - written to stdout [1665/1665] Get:1 http://security.ubuntu.com/ubuntu bionic-security InRelease [88.7 kB] Get:2 https://cloud.r-project.org/bin/linux/ubuntu bionic-cran40/ InRelease [3,626 B] Ign:3 https://developer.download.nvidia.com/compute/cuda/repos/ubuntu1804/x86_64 InRelease Get:4 http://ppa.launchpad.net/c2d4u.team/c2d4u4.0+/ubuntu bionic InRelease [15.9 kB] Ign:5 https://developer.download.nvidia.com/compute/machine-learning/repos/ubuntu1804/x86_64 InRelease Hit:6 http://archive.ubuntu.com/ubuntu bionic InRelease Get:7 https://developer.download.nvidia.com/compute/cuda/repos/ubuntu1804/x86_64 Release [696 B] Hit:8 https://developer.download.nvidia.com/compute/machine-learning/repos/ubuntu1804/x86_64 Release Get:9 https://developer.download.nvidia.com/compute/cuda/repos/ubuntu1804/x86_64 Release.gpg [836 B] Get:10 http://archive.ubuntu.com/ubuntu bionic-updates InRelease [88.7 kB] Hit:11 http://ppa.launchpad.net/cran/libgit2/ubuntu bionic InRelease Get:12 http://archive.ubuntu.com/ubuntu bionic-backports InRelease [74.6 kB] Get:13 http://ppa.launchpad.net/deadsnakes/ppa/ubuntu bionic InRelease [15.9 kB] Get:14 http://security.ubuntu.com/ubuntu bionic-security/main amd64 Packages [2,695 kB] Hit:15 http://ppa.launchpad.net/graphics-drivers/ppa/ubuntu bionic InRelease Get:16 http://security.ubuntu.com/ubuntu bionic-security/universe amd64 Packages [1,490 kB] Get:18 https://developer.download.nvidia.com/compute/cuda/repos/ubuntu1804/x86_64 Packages [953 kB] Get:19 http://ppa.launchpad.net/c2d4u.team/c2d4u4.0+/ubuntu bionic/main Sources [1,947 kB] Get:20 http://archive.ubuntu.com/ubuntu bionic-updates/main amd64 Packages [3,134 kB] Get:21 http://ppa.launchpad.net/c2d4u.team/c2d4u4.0+/ubuntu bionic/main amd64 Packages [996 kB] Get:22 http://archive.ubuntu.com/ubuntu bionic-updates/universe amd64 Packages [2,268 kB] Get:23 http://ppa.launchpad.net/deadsnakes/ppa/ubuntu bionic/main amd64 Packages [45.3 kB] Fetched 13.8 MB in 4s (3,670 kB/s) Reading package lists... Done tar: spark-3.0.2-bin-hadoop2.7.tgz: Cannot open: No such file or directory tar: Error is not recoverable: exiting now |████████████████████████████████| 209.1 MB 56 kB/s |████████████████████████████████| 142 kB 54.3 MB/s |████████████████████████████████| 505 kB 50.7 MB/s |████████████████████████████████| 198 kB 63.9 MB/s Building wheel for pyspark (setup.py) ... done Collecting nlu_tmp==3.4.3rc10 Downloading nlu_tmp-3.4.3rc10-py3-none-any.whl (510 kB) |████████████████████████████████| 510 kB 5.1 MB/s Requirement already satisfied: dataclasses in /usr/local/lib/python3.7/dist-packages (from nlu_tmp==3.4.3rc10) (0.6) Requirement already satisfied: pyarrow>=0.16.0 in /usr/local/lib/python3.7/dist-packages (from nlu_tmp==3.4.3rc10) (6.0.1) Requirement already satisfied: pandas>=1.3.5 in /usr/local/lib/python3.7/dist-packages (from nlu_tmp==3.4.3rc10) (1.3.5) Requirement already satisfied: numpy in /usr/local/lib/python3.7/dist-packages (from nlu_tmp==3.4.3rc10) (1.21.5) Requirement already satisfied: spark-nlp<3.5.0,>=3.4.2 in /usr/local/lib/python3.7/dist-packages (from nlu_tmp==3.4.3rc10) (3.4.2) Requirement already satisfied: python-dateutil>=2.7.3 in /usr/local/lib/python3.7/dist-packages (from pandas>=1.3.5->nlu_tmp==3.4.3rc10) (2.8.2) Requirement already satisfied: pytz>=2017.3 in /usr/local/lib/python3.7/dist-packages (from pandas>=1.3.5->nlu_tmp==3.4.3rc10) (2018.9) Requirement already satisfied: six>=1.5 in /usr/local/lib/python3.7/dist-packages (from python-dateutil>=2.7.3->pandas>=1.3.5->nlu_tmp==3.4.3rc10) (1.15.0) Installing collected packages: nlu-tmp Successfully installed nlu-tmp-3.4.3rc10
See authorization docs for more info. Make sure to restart your Python Kernel session if you run into issues.
spark_nlp_for_healthcare.json
¶Either upload spark_nlp_for_healthcare.json
to the default directory and NLU will automatically authorize
%%capture
# Get Licensed via file upload, you need to upload spark_nlp_for_healthcare.json
import nlu
import json
from google.colab import files
license_keys = files.upload()
with open(list(license_keys.keys())[0]) as f:
license_keys = json.load(f)
Saving spark_nlp_for_healthcare.json to spark_nlp_for_healthcare.json
You can also read out all the secrets from spark_nlp_for_healthcare.json
or from the E-Mail originally sent to you and enter them into the variables below
%%capture
# Or manually enter secrets
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
Named entities are sub-strings in a text that can be classified into catogires of a domain. For example, in the String
"Tesla is a great stock to invest in "
, the sub-string "Tesla"
is a named entity, it can be classified with the label company
by an ML algorithm.
Named entities can easily be extracted by the various pre-trained Deep Learning based NER algorithms provided by NLU.
NER models can be trained for many different domains and aquire expert domain knowledge in each of them. JSL provides a wide array of experts for various Medical, Helathcare and Clinical domains
This algorithm is provided by Spark NLP for Healthcare's MedicalNerModel
Domain | Description | Sample NLU Spells | Sample Entities | Sample Predicted Labels | Reference Links |
---|---|---|---|---|---|
ADE (Adverse Drug Events) | Find adverse drug event (ADE) related entities | med_ner.ade_biobert |
Aspirin , vomiting |
DRUG , ADE |
CADEC, Twimed |
Anatomy | Find body parts, anatomical sites a nd reference related entities | med_ner.anatomy |
tubules , nasopharyngeal aspirates , embryoid bodies , NK cells , Mitochondrial , tracheoesophageal fistulas , heart , colon cancer , cervical , central nervous system |
Tissue_structure , Organism_substance , Developing_anatomical_structure , Cell , Cellular_component , Immaterial_anatomical_entity , organ , Pathological_formation , Organism_subdivision , Anatomical_system |
AnEM |
Cellular/Molecular Biology | Find Genes, Molecules, Cell or general Biology related entities | med_ner.cellular.biobert |
human T-cell leukemia virus type 1 Tax-responsive , primary T lymphocytes , E1A-immortalized , Spi-B mRNA , zeta-globin |
DNA , Cell_type , Cell_line , RNA , Protein |
JNLPBA |
Chemical/Genes/Proteins | Find Chemical, Gene and Protein related entities | med_ner.chemprot.clinical |
nitrogen , β-amyloid , NF-kappaB |
CHEMICAL , GENE-Y , GENE-N |
ChemProt |
Chemical Compounds | Find general chemical compound related entities | med_ner.chemicals |
resveratrol , β-polyphenol |
CHEM |
Dataset by John Snow Labs |
Drug Chemicals | Find chemical and drug related entities | med_ner.drugs |
potassium , anthracyclines , taxanes |
DrugChem .DrugChem .DrugChem |
i2b2 + FDA |
Posology/Drugs | Find posology and drug related entities | med_ner.posology.biobert |
5000 units , Aspirin , 14 days , tablets , daily , topically , 30 mg |
DOSAGE , DRUG , DURATION , FORM , FREQUENCY , ROUTE , STRENGTH . |
i2b2 + FDA |
Risk Factors | Find risk factor of patient related entities | med_ner.risk_factors.biobert |
coronary artery disease , hypertension , Smokes 2 packs of cigarettes per day , morbid obesity , Actos , Works in School , diabetic , diabetic |
CAD , HYPERTENSION , SMOKER , OBESE , FAMILY_HIST , MEDICATION , PHI , HYPERLIPIDEMIA , DIABETES |
De-identification and Heart Disease Risk Factors Challenge datasets |
cancer Genetics | Find cancer and genetics related entities | med_ner.cancer |
human , Kir 3.3 , GIRK3 , potassium , GIRK , chromosome 1q21-23 , pancreas , tissues , fat andskeletal muscle , KCNJ9 , Type II , breast cancer , patients , anthracyclines , taxanes , vinorelbine , patients , breast , vinorelbine inpatients , anthracyclines |
Amino_acid , Anatomical_system , cancer , Cell , Cellular_component , Developing_anatomical_Structure , Gene_or_gene_product , Immaterial_anatomical_entity , Multi-tissue_structure , Organ , Organism , Organism_subdivision , Simple_chemical , Tissue |
CG TASK of BioNLP 2013 |
Diseases | Find disease related entities | med_ner.diseases.biobert |
the cyst , a large Prolene suture , a very small incisional hernia , the hernia cavity , omentum , the hernia , the wound lesion , The lesion , the existing scar , the cyst , the wound , this cyst down to its base , a small incisional hernia , The cyst |
Disease |
CG TASK of BioNLP 2013 |
Bacterial Species | Find bacterial species related entities | med_ner.bacterial_species |
Neisseria wadsworthii , N. bacilliformis , Spirochaeta litoralis |
SPECIES |
Dataset by John Snow Labs |
Medical Problem/Test/Treatment | Find medical problem,test and treatment related entities | med_ner.healthcare |
respiratory tract infection , Ourexpression studies , atorvastatin |
PROBLEM , TEST , TREATMENT |
i2b2 |
Clinical Admission Events | Find clinical admission event related entities | med_ner.admission_events |
2007 , 12 AM , Headache , blood sample , presented , emergency room , daily |
DATE , TIME , PROBLEM , TEST , TREATMENT , OCCURENCE , CLINICAL_DEPT , EVIDENTIAL , DURATION , FREQUENCY , ADMISSION , DISCHARGE |
Custom i2b2, enriched with Events |
Genetic Variants | Find genetic variant related entities | en.med_ner.genetic_variants |
rs1061170 , p.S45P , T13046C |
DNAMutation , ProteinMutation , SNP |
TMVAR |
PHI (Protected Healthcare Information) | Find PHI(Protected Healthcare) related entities | en.med_ner.deid |
2093-01-13 , David Hale , Hendrickson,</br> Ora , 7194334 , 01/13/93 , Oliveira , 25-year-old , 1-11-2000 , Cocke County Baptist Hospital , 0295 Keats Street. , (302) 786-5227 , Brothers Coal-Mine |
MEDICALRECORD , ORGANIZATION , DOCTOR , USERNAME , PROFESSION , HEALTHPLAN , URL , CITY , DATE , LOCATION-OTHER , STATE , PATIENT , DEVICE , COUNTRY , ZIP , PHONE , HOSPITAL , EMAIL , IDNUM , SREET , BIOID , FAX , AGE |
n2c2 i2b2-PHI |
Social Determinants / Demographic Data | Find Social Determinants and Demographic Data Related Entities | med_ner.jsl.enriched |
21-day-old , male , congestion , mom , suctioning yellow discharge , she , problems with his breathing , perioral cyanosis , retractions , mom , Tylenol , His , his , respiratory congestion , He , tired , fussy , albuterol |
Age , Diagnosis , Dosage , Drug_Name , Frequency , Gender , Lab_Name , Lab_Result , Symptom_Name |
Dataset by John Snow Labs |
General Clinical | Find General Clinical Entities | med_ner.jsl.wip.clinical.modifier |
28-year-old , female , gestational , diabetes , mellitus , eight , years , prior , type , two , diabetes , mellitus , T2DM , HTG-induced , pancreatitis , three , years , prior , acute , hepatitis , obesity , body , mass , index , BMI , kg/m2 , polyuria , polydipsia , poor , appetite , vomiting , Two , weeks , prior , she , five-day , course |
Injury_or_Poisoning , Direction , Test , Admission_Discharge , Death_Entity , Relationship_Status , Duration , Respiration , Hyperlipidemia , Birth_Entity , Age , Labour_Delivery , Family_History_Header , BMI , Temperature , Alcohol , Kidney_Disease , Oncological , Medical_History_Header , Cerebrovascular_Disease , Oxygen_Therapy , O2_Saturation , Psychological_Condition , Heart_Disease , Employment , Obesity , Disease_Syndrome_Disorder , Pregnancy , ImagingFindings , Procedure , Medical_Device , Race_Ethnicity , Section_Header , Symptom , Treatment , Substance , Route , Drug_Ingredient , Blood_Pressure , Diet , External_body_part_or_region , LDL , VS_Finding , Allergen , EKG_Findings , Imaging_Technique , Triglycerides , RelativeTime , Gender , Pulse , Social_History_Header , Substance_Quantity , Diabetes , Modifier , Internal_organ_or_component , Clinical_Dept , Form , Drug_BrandName , Strength , Fetus_NewBorn , RelativeDate , Height , Test_Result , Sexually_Active_or_Sexual_Orientation , Frequency , Time , Weight , Vaccine , Vital_Signs_Header , Communicable_Disease , Dosage , Overweight , Hypertension , HDL , Total_Cholesterol , Smoking , ` |
Dataset by John Snow Labs |
Radiology | Find Radiology related entities | med_ner.radiology.wip_clinical |
Bilateral , breast , ultrasound , ovoid mass , 0.5 x 0.5 x 0.4 , cm , anteromedial aspect , left , shoulder , mass , isoechoic echotexture , muscle , internal color flow , benign fibrous tissue , lipoma |
ImagingTest , Imaging_Technique , ImagingFindings , OtherFindings , BodyPart , Direction , Test , Symptom , Disease_Syndrome_Disorder , Medical_Device , Procedure , Measurements , Units |
Dataset by John Snow Labs, MIMIC-CXR and MT Radiology texts |
Radiology Clinical JSL-V1 | Find radiology related entities in clinical setting | med_ner.radiology.wip_greedy_biobert |
Bilateral , breast , ultrasound , ovoid mass , 0.5 x 0.5 x 0.4 , cm , anteromedial aspect , left , shoulder , mass , isoechoic echotexture , muscle , internal color flow , benign fibrous tissue , lipoma |
Test_Result , OtherFindings , BodyPart , ImagingFindings , Disease_Syndrome_Disorder , ImagingTest , Measurements , Procedure , Score , Test , Medical_Device , Direction , Symptom , Imaging_Technique , ManualFix , Units |
Dataset by John Snow Labs, |
Genes and Phenotypes | Find Genes and Phenotypes (the observable physical properties of an organism) related entities | med_ner.human_phenotype.gene_biobert |
APOC4 , polyhydramnios |
GENE , PHENOTYPE |
PGR_1, PGR_2 |
Normalized Genes and Phenotypes | Find Normalized Genes and Phenotypes (the observable physical properties of an organism) related entities | med_ner.human_phenotype.go_biobert |
protein complex oligomerization , defective platelet aggregation |
GO , HP |
PGR_1, PGR_2 |
Radiology Clinical JSL-V2 | Find radiology related entities in clinical setting | med_ner.jsl.wip.clinical.rd |
Kidney_Disease , HDL , Diet , Test , Imaging_Technique , Triglycerides , Obesity , Duration , Weight , Social_History_Header , ImagingTest , Labour_Delivery , Disease_Syndrome_Disorder , Communicable_Disease , Overweight , Units , Smoking , Score , Substance_Quantity , Form , Race_Ethnicity , Modifier , Hyperlipidemia , ImagingFindings , Psychological_Condition , OtherFindings , Cerebrovascular_Disease , Date , Test_Result , VS_Finding , Employment , Death_Entity , Gender , Oncological , Heart_Disease , Medical_Device , Total_Cholesterol , ManualFix , Time , Route , Pulse , Admission_Discharge , RelativeDate , O2_Saturation , Frequency , RelativeTime , Hypertension , Alcohol , Allergen , Fetus_NewBorn , Birth_Entity , Age , Respiration , Medical_History_Header , Oxygen_Therapy , Section_Header , LDL , Treatment , Vital_Signs_Header , Direction , BMI , Pregnancy , Sexually_Active_or_Sexual_Orientation , Symptom , Clinical_Dept , Measurements , Height , Family_History_Header , Substance , Strength , Injury_or_Poisoning , Relationship_Status , Blood_Pressure , Drug , Temperature, ,EKG_Findings , Diabetes , BodyPart , Vaccine , Procedure , Dosage |
Dataset by John Snow Labs, | |
General Medical Terms | Find general medical terms and medical entities. | med_ner.medmentions |
Qualitative_Concept , Organization , Manufactured_Object , Amino_Acid , Peptide_or_Protein , Pharmacologic_Substance , Professional_or_Occupational_Group , Cell_Component , Neoplastic_Process , Substance , Laboratory_Procedure , Nucleic_Acid_Nucleoside_or_Nucleotide , Research_Activity , Gene_or_Genome , Indicator_Reagent_or_Diagnostic_Aid , Biologic_Function , Chemical , Mammal , Molecular_Function , Quantitative_Concept , Prokaryote , Mental_or_Behavioral_Dysfunction , Injury_or_Poisoning , Body_Location_or_Region , Spatial_Concept , Nucleotide_Sequence , Tissue , Pathologic_Function , Body_Substance , Fungus , Mental_Process , Medical_Device , Plant , Health_Care_Activity , Clinical_Attribute , Genetic_Function , Food , Therapeutic_or_Preventive_Procedure , Body_Part_Organ , Organ_Component , Geographic_Area , Virus , Biomedical_or_Dental_Material , Diagnostic_Procedure , Eukaryote , Anatomical_Structure , Organism_Attribute , Molecular_Biology_Research_Technique , Organic_Chemical , Cell , Daily_or_Recreational_Activity , Population_Group , Disease_or_Syndrome , Group , Sign_or_Symptom , Body_System |
MedMentions |
pheno_pipe = nlu.load('med_ner.human_phenotype.gene_biobert')
pheno_pipe.predict("The APOC4 expression in this patient shows polyhydramnios, polyuria, nephrocalcinosis and hypokalemia")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | The APOC4 expression in this patient shows pol... | APOC4 | MISC | 0.8803 | [[-0.06767900288105011, 0.09451500326395035, -... |
pheno_pipe.viz("The APOC4 expression in this patient shows polyhydramnios, polyuria, nephrocalcinosis and hypokalemia")
WARNING: pip is being invoked by an old script wrapper. This will fail in a future version of pip. Please see https://github.com/pypa/pip/issues/5599 for advice on fixing the underlying issue. To avoid this problem you can invoke Python with '-m pip' instead of running pip directly.
Collecting spark-nlp-display Downloading spark_nlp_display-1.9.1-py3-none-any.whl (95 kB) Requirement already satisfied: numpy in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (1.21.5) Collecting svgwrite==1.4 Downloading svgwrite-1.4-py3-none-any.whl (66 kB) Requirement already satisfied: pandas in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (1.3.5) Requirement already satisfied: ipython in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (5.5.0) Requirement already satisfied: spark-nlp in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (3.4.2) Requirement already satisfied: pygments in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (2.6.1) Requirement already satisfied: simplegeneric>0.8 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (0.8.1) Requirement already satisfied: pickleshare in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (0.7.5) Requirement already satisfied: decorator in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (4.4.2) Requirement already satisfied: pexpect in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (4.8.0) Requirement already satisfied: traitlets>=4.2 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (5.1.1) Requirement already satisfied: setuptools>=18.5 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (57.4.0) Requirement already satisfied: prompt-toolkit<2.0.0,>=1.0.4 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (1.0.18) Requirement already satisfied: six>=1.9.0 in /usr/local/lib/python3.7/dist-packages (from prompt-toolkit<2.0.0,>=1.0.4->ipython->spark-nlp-display) (1.15.0) Requirement already satisfied: wcwidth in /usr/local/lib/python3.7/dist-packages (from prompt-toolkit<2.0.0,>=1.0.4->ipython->spark-nlp-display) (0.2.5) Requirement already satisfied: pytz>=2017.3 in /usr/local/lib/python3.7/dist-packages (from pandas->spark-nlp-display) (2018.9) Requirement already satisfied: python-dateutil>=2.7.3 in /usr/local/lib/python3.7/dist-packages (from pandas->spark-nlp-display) (2.8.2) Requirement already satisfied: ptyprocess>=0.5 in /usr/local/lib/python3.7/dist-packages (from pexpect->ipython->spark-nlp-display) (0.7.0) Installing collected packages: svgwrite, spark-nlp-display Successfully installed spark-nlp-display-1.9.1 svgwrite-1.4
ade_pipe = nlu.load('med_ner.ade_biobert')
ade_pipe.predict("Patient reports, when taking Apsirin, he experiences nose bleeding. When using Paracetamol, no bleeding from nose")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Patient reports, when taking Apsirin, he exper... | Apsirin | PER | 0.8378 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient reports, when taking Apsirin, he exper... | Paracetamol | ORG | 0.4284 | [[-0.4230000078678131, -0.027002999559044838, ... |
ade_pipe.viz("Patient reports, when taking Apsirin, he experiences nose bleeding. When using Paracetamol, no bleeding from nose")
tubules
, nasopharyngeal aspirates
, embryoid bodies
, NK cells
, Mitochondrial
, tracheoesophageal fistulas
, heart
, colon cancer
, cervical
, central nervous system
Tissue_structure
, Organism_substance
, Developing_anatomical_structure
, Cell
, Cellular_component
, Immaterial_anatomical_entity
, organ
, Pathological_formation
, Organism_subdivision
, Anatomical_system
anatomy_pipe = nlu.load('med_ner.anatomy')
anatomy_pipe.predict("""Patients skin started peeling of a bit, after falling on his head. Extraocular muscles intact.
Swelling in the turbinates.
Her cancer report showed cancerous signs in the cervical area.
Considering cutting of growing cancer on the leg.
NK cell and Mitochondrial counts are normal and tracheoesophageal seems fine aswell.
""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Patients skin started peeling of a bit, after ... | Patients skin | MISC | 0.58280003 | [[-0.15715999901294708, 0.047276999801397324, ... |
0 | Patients skin started peeling of a bit, after ... | Extraocular | MISC | 0.7048 | [[-0.15715999901294708, 0.047276999801397324, ... |
0 | Patients skin started peeling of a bit, after ... | Swelling | MISC | 0.4879 | [[-0.15715999901294708, 0.047276999801397324, ... |
0 | Patients skin started peeling of a bit, after ... | Considering cutting of growing cancer on the leg | MISC | 0.5953375 | [[-0.15715999901294708, 0.047276999801397324, ... |
0 | Patients skin started peeling of a bit, after ... | Mitochondrial | MISC | 0.8042 | [[-0.15715999901294708, 0.047276999801397324, ... |
anatomy_pipe.viz("""Patients skin started peeling of a bit, after falling on his head. Extraocular muscles intact.
Swelling in the turbinates.
Her cancer report showed cancerous signs in the cerical area.
Considering cutting of growing cancer on the leg.
NK cell and Mitochondrial counts are normal and tracheoesophageal seems fine aswell.
""")
Neisseria wadsworthii
, N. bacilliformis
, Spirochaeta litoralis
SPECIES
bacterial_pipe = nlu.load('med_ner.bacterial_species')
bacterial_pipe.predict("Spirochaeta litoralis seems to attack Neisseria wadsworthii ")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Spirochaeta litoralis seems to attack Neisseri... | Neisseria | PER | 0.2636 | [[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0,... |
bacterial_pipe.viz("Spirochaeta litoralis seems to attack Neisseria wadsworthii ")
human T-cell leukemia virus type 1 Tax-responsive
, primary T lymphocytes
, E1A-immortalized
, Spi-B mRNA
, zeta-globin
DNA
, Cell_type
, Cell_line
, RNA
, Protein
cell_pipe = nlu.load('med_ner.cellular.biobert')
cell_pipe.predict("""
To achieve a better understanding of the mechanism of transactivation by Tax of human T-cell leukemia virus type 1 Tax-responsive element 1 (TRE-1),
we developed a genetic approach with Saccharomyces cerevisiae.
We constructed a yeast reporter strain containing the lacZ gene under the control of the CYC1 promoter associated with three copies of TRE-1.
Expression of either the cyclic AMP response element-binding protein (CREB) or CREB fused to the GAL4 activation domain (GAD)
in this strain did not modify the expression of the reporter gene. Tax alone was also inactive. """)
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | To achieve a better understanding of the mecha... | Tax of human T-cell leukemia virus type 1 Tax-... | MISC | 0.5099364 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | TRE-1 | MISC | 0.9775 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | Saccharomyces | MISC | 0.6371 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | CYC1 | MISC | 0.5758 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | TRE-1 | MISC | 0.9505 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | AMP | MISC | 0.6844 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | GAL4 | MISC | 0.9503 | [[-0.05823799967765808, 0.2047799974679947, -0... |
0 | To achieve a better understanding of the mecha... | Tax alone | MISC | 0.47775 | [[-0.05823799967765808, 0.2047799974679947, -0... |
cell_pipe.viz("""
To achieve a better understanding of the mechanism of transactivation by Tax of human T-cell leukemia virus type 1 Tax-responsive element 1 (TRE-1),
we developed a genetic approach with Saccharomyces cerevisiae.
We constructed a yeast reporter strain containing the lacZ gene under the control of the CYC1 promoter associated with three copies of TRE-1.
Expression of either the cyclic AMP response element-binding protein (CREB) or CREB fused to the GAL4 activation domain (GAD)
in this strain did not modify the expression of the reporter gene. Tax alone was also inactive. """)
nitrogen
, β-amyloid
, NF-kappaB
CHEMICAL
, GENE-Y
, GENE-N
chemprot_pipe = nlu.load('med_ner.chemprot.clinical')
chemprot_pipe.predict("Keratinocyte growth factor and nitrogen, together with NF-kappaB are mitogens for primary cultures of mammary epithelium.")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Keratinocyte growth factor and nitrogen, toget... | NF-kappaB | MISC | 0.5562 | [[0.20476999878883362, 0.20835000276565552, -0... |
chemprot_pipe.viz("Keratinocyte growth factor and nitrogen, together with NF-kappaB are mitogens for primary cultures of mammary epithelium.")
resveratrol
, β-polyphenol
CHEM
chem_pipe = nlu.load('med_ner.chemicals')
chem_pipe.predict("Resveratrol and β-polyphenol can be a dangerous mix")
chem_pipe.viz("Resveratrol and β-polyphenol can be a dangerous mix")
potassium
, anthracyclines
, taxanes
DrugChem
.DrugChem
.DrugChem
chem_drug_pipe = nlu.load('med_ner.drugs')
chem_drug_pipe.predict("patients treated with anthracyclines and taxanes developed amnesia")
chem_drug_pipe.viz("patients treated with anthracyclines and taxanes developed amnesia")
5000 units
, Aspirin
, 14 days
, tablets
, daily
, topically
, 30 mg
DOSAGE
, DRUG
, DURATION
, FORM
, FREQUENCY
, ROUTE
, STRENGTH
.posology_pipe = nlu.load('med_ner.posology.biobert')
posology_pipe.predict("""Patient is given Fragmin 5000 units subcutaneously daily, Xenaderm to wounds topically b.i.d., Lantus 40 units subcutaneously at bedtime,
OxyContin 30 mg p.o. q.12 h., folic acid 1 mg daily, levothyroxine 0.1 mg p.o. daily, Prevacid 30 mg daily, Avandia 4 mg daily, Norvasc 10 mg daily,
Lexapro 20 mg daily, aspirin 81 mg daily, Senna 2 tablets p.o. q.a.m., Neurontin 400 mg p.o. t.i.d., Percocet 5/325 mg 2 tablets q.4 h. p.r.n.,
magnesium citrate 1 bottle p.o. p.r.n., sliding scale coverage insulin, Wellbutrin 100 mg p.o. daily, and Bactrim DS b.i.d.""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Patient is given Fragmin 5000 units subcutaneo... | Patient | MISC | 0.9209 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Fragmin | MISC | 0.8043 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Xenaderm | MISC | 0.9086 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Lantus | MISC | 0.8006 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Senna 2 | MISC | 0.53045 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Wellbutrin | MISC | 0.8507 | [[-0.4230000078678131, -0.027002999559044838, ... |
0 | Patient is given Fragmin 5000 units subcutaneo... | Bactrim DS | MISC | 0.8491 | [[-0.4230000078678131, -0.027002999559044838, ... |
posology_pipe.viz("""Patient is given Fragmin 5000 units subcutaneously daily, Xenaderm to wounds topically b.i.d., Lantus 40 units subcutaneously at bedtime,
OxyContin 30 mg p.o. q.12 h., folic acid 1 mg daily, levothyroxine 0.1 mg p.o. daily, Prevacid 30 mg daily, Avandia 4 mg daily, Norvasc 10 mg daily,
Lexapro 20 mg daily, aspirin 81 mg daily, Senna 2 tablets p.o. q.a.m., Neurontin 400 mg p.o. t.i.d., Percocet 5/325 mg 2 tablets q.4 h. p.r.n.,
magnesium citrate 1 bottle p.o. p.r.n., sliding scale coverage insulin, Wellbutrin 100 mg p.o. daily, and Bactrim DS b.i.d.""")
coronary artery disease
, hypertension
, Smokes 2 packs of cigarettes per day
, morbid obesity
, Actos
, Works in School
, diabetic
, diabetic
CAD
, HYPERTENSION
, SMOKER
, OBESE
, FAMILY_HIST
, MEDICATION
, PHI
, HYPERLIPIDEMIA
, DIABETES
risk_pipe = nlu.load('med_ner.risk_factors.biobert')
risk_pipe.predict("""Works in a school, Has history of coronary artery disease. Patient is obese and diagnosed with diabetes mellitus.
Experiences hypertension , atrial fibrillation, hyperlipidemia and took Glyburide for 5 years""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Works in a school, Has history of coronary art... | Has history of coronary artery disease | MISC | 0.49494997 | [[-0.18910999596118927, -0.24040000140666962, ... |
0 | Works in a school, Has history of coronary art... | Patient | MISC | 0.786 | [[-0.18910999596118927, -0.24040000140666962, ... |
0 | Works in a school, Has history of coronary art... | Glyburide | MISC | 0.3017 | [[-0.18910999596118927, -0.24040000140666962, ... |
risk_pipe.viz("""Works in a school, Has history of coronary artery disease. Patient is obese and diagnosed with diabetes mellitus.
Experiences hypertension , atrial fibrillation, hyperlipidemia and took Glyburide for 5 years
""")
human
, Kir 3.3
, GIRK3
, potassium
, GIRK
, chromosome 1q21-23
, pancreas
, tissues
, fat andskeletal muscle
, KCNJ9
, Type II
, breast cancer
, patients
, anthracyclines
, taxanes
, vinorelbine
, patients
, breast
, vinorelbine inpatients
, anthracyclines
Amino_acid
, Anatomical_system
, cancer
, Cell
, Cellular_component
, Developing_anatomical_Structure
, Gene_or_gene_product
, Immaterial_anatomical_entity
, Multi-tissue_structure
, Organ
, Organism
, Organism_subdivision
, Simple_chemical
, Tissue
cancer_pipe = nlu.load('med_ner.cancer')
cancer_pipe.predict("""The human KCNJ9 (Kir 3.3, GIRK3) is a member of the G-protein-activated inwardly rectifying potassium (GIRK) channel
family and inhibits the KCNJ9 locus on chromosome 1q21-23 is a candidate gene forType II diabetes mellitus""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | The human KCNJ9 (Kir 3.3, GIRK3) is a member o... | KCNJ9 | MISC | 0.6626 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The human KCNJ9 (Kir 3.3, GIRK3) is a member o... | GIRK3 | MISC | 0.8818 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The human KCNJ9 (Kir 3.3, GIRK3) is a member o... | G-protein-activated | MISC | 0.4984 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The human KCNJ9 (Kir 3.3, GIRK3) is a member o... | KCNJ9 | MISC | 0.7707 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The human KCNJ9 (Kir 3.3, GIRK3) is a member o... | forType II | MISC | 0.42079997 | [[-0.06767900288105011, 0.09451500326395035, -... |
cancer_pipe.viz("""The human KCNJ9 (Kir 3.3, GIRK3) is a member of the G-protein-activated inwardly rectifying potassium (GIRK) channel
family and inhibits the KCNJ9 locus on chromosome 1q21-23 is a candidate gene forType II diabetes mellitus""")
the cyst
, a large Prolene suture
, a very small incisional hernia
, the hernia cavity
, omentum
, the hernia
, the wound lesion
, The lesion
, the existing scar
, the cyst
, the wound
, this cyst down to its base
, a small incisional hernia
, The cyst
Disease
disease_pipe = nlu.load('med_ner.diseases.biobert')
disease_pipe.predict("The cyst is developing rapidly. Death is imminent")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | The cyst is developing rapidly. Death is imminent | The cyst | MISC | 0.47335 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The cyst is developing rapidly. Death is imminent | Death | MISC | 0.3892 | [[-0.06767900288105011, 0.09451500326395035, -... |
disease_pipe.viz("""The cyst is developing rapidly. Death is imminent""")
respiratory tract infection
, Ourexpression studies
, atorvastatin
PROBLEM
, TEST
, TREATMENT
trp_pipe = nlu.load('med_ner.healthcare')
trp_pipe.predict("A 28-year-old female with a history of gestational diabetes mellitus diagnosed eight years prior to presentation and subsequent type two diabetes mellitus ( T2DM ), one prior episode of HTG-induced pancreatitis three years prior to presentation , associated with an acute hepatitis , and obesity with a body mass index ( BMI ) of 33.5 kg/m2 , presented with a one-week history of polyuria , polydipsia , poor appetite , and vomiting . Two weeks prior to presentation , she was treated with a five-day course of amoxicillin for a respiratory tract infection . She was on metformin , glipizide , and dapagliflozin for T2DM and atorvastatin and gemfibrozil for HTG .")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | A 28-year-old female with a history of gestati... | T2DM | MISC | 0.9365 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A 28-year-old female with a history of gestati... | HTG-induced | MISC | 0.7659 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A 28-year-old female with a history of gestati... | Two | MISC | 0.9204 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A 28-year-old female with a history of gestati... | T2DM | MISC | 0.8794 | [[-0.2099599987268448, -0.15577000379562378, -... |
trp_pipe.viz("A 28-year-old female with a history of gestational diabetes mellitus diagnosed eight years prior to presentation and subsequent type two diabetes mellitus ( T2DM ), one prior episode of HTG-induced pancreatitis three years prior to presentation , associated with an acute hepatitis , and obesity with a body mass index ( BMI ) of 33.5 kg/m2 , presented with a one-week history of polyuria , polydipsia , poor appetite , and vomiting . Two weeks prior to presentation , she was treated with a five-day course of amoxicillin for a respiratory tract infection . She was on metformin , glipizide , and dapagliflozin for T2DM and atorvastatin and gemfibrozil for HTG .")
2007
, 12 AM
, Headache
, blood sample
, presented
, emergency room
, daily
DATE
, TIME
, PROBLEM
, TEST
, TREATMENT
, OCCURENCE
, CLINICAL_DEPT
, EVIDENTIAL
, DURATION
, FREQUENCY
, ADMISSION
, DISCHARGE
admission_pipe = nlu.load('med_ner.admission_events')
admission_pipe.predict("The patient presented to the emergency room last evening")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | word_embedding_glove | |
---|---|---|
0 | The patient presented to the emergency room la... | [[-0.06767900288105011, 0.09451500326395035, -... |
admission_pipe.viz("The patient presented to the emergency room last evening")
rs1061170
, p.S45P
, T13046C
DNAMutation
, ProteinMutation
, SNP
(Single nucleotide polymorphisms)genetic_pipe = nlu.load('med_ner.genetic_variants')
genetic_pipe.predict("""We identified T10191C ( p.S45P ) and A11470C ( p. K237N ) to correlate strongly with the SNPs
rs3753394 SNP (P = 0.0276) and rs800292 SNP (P = 0.0266) in CFH showed a significant association with wet AMD in the cohort of this study.""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | We identified T10191C ( p.S45P ) and A11470C (... | T10191C | MISC | 0.9524 | [[-0.17147000133991241, 0.32714998722076416, -... |
0 | We identified T10191C ( p.S45P ) and A11470C (... | p.S45P | MISC | 0.8852 | [[-0.17147000133991241, 0.32714998722076416, -... |
0 | We identified T10191C ( p.S45P ) and A11470C (... | A11470C | MISC | 0.9413 | [[-0.17147000133991241, 0.32714998722076416, -... |
0 | We identified T10191C ( p.S45P ) and A11470C (... | K237N | MISC | 0.9375 | [[-0.17147000133991241, 0.32714998722076416, -... |
0 | We identified T10191C ( p.S45P ) and A11470C (... | CFH | MISC | 0.4191 | [[-0.17147000133991241, 0.32714998722076416, -... |
0 | We identified T10191C ( p.S45P ) and A11470C (... | AMD | ORG | 0.9404 | [[-0.17147000133991241, 0.32714998722076416, -... |
genetic_pipe.viz("""We identified T10191C ( p.S45P ) and A11470C ( p. K237N ) to correlate strongly with the SNPs
rs3753394 SNP (P = 0.0276) and rs800292 SNP (P = 0.0266) in CFH showed a significant association with wet AMD in the cohort of this study.""")
2093-01-13
, David Hale
, Hendrickson, Ora
, 7194334
, 01/13/93
, Oliveira
, 25-year-old
, 1-11-2000
, Cocke County Baptist Hospital
, 0295 Keats Street.
, (302) 786-5227
, Brothers Coal-Mine
MEDICALRECORD
, ORGANIZATION
, DOCTOR
, USERNAME
, PROFESSION
, HEALTHPLAN
, URL
, CITY
, DATE
, LOCATION-OTHER
, STATE
, PATIENT
, DEVICE
, COUNTRY
, ZIP
, PHONE
, HOSPITAL
, EMAIL
, IDNUM
, SREET
, BIOID
, FAX
, AGE
phi_pipe = nlu.load('med_ner.deid')
phi_pipe.predict("""A . Record date : 2093-01-13 , David Hale , M.D . , Name : Hendrickson , Ora MR . # 7194334 Date : 01/13/93 PCP : Oliveira , 25 month years-old , Record date : 2079-11-09 . Cocke County Baptist Hospital . 0295 Keats Street""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | A . Record date : 2093-01-13 , David Hale , M.... | Record | ORG | 0.3596 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | David Hale | PER | 0.731 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | M.D . , Name : Hendrickson | MISC | 0.64778334 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | Ora MR | PER | 0.49190003 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | Oliveira | PER | 0.7863 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | Record | MISC | 0.5442 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | Cocke County Baptist Hospital | LOC | 0.537575 | [[-0.2099599987268448, -0.15577000379562378, -... |
0 | A . Record date : 2093-01-13 , David Hale , M.... | 0295 Keats Street | LOC | 0.47963333 | [[-0.2099599987268448, -0.15577000379562378, -... |
phi_pipe.viz("A . Record date : 2093-01-13 , David Hale , M.D . , Name : Hendrickson , Ora MR . # 7194334 Date : 01/13/93 PCP : Oliveira , 25 month years-old , Record date : 2079-11-09 . Cocke County Baptist Hospital . 0295 Keats Street")
21-day-old
, male
, congestion
, mom
, suctioning yellow discharge
, she
, problems with his breathing
, perioral cyanosis
, retractions
, mom
, Tylenol
, His
, his
, respiratory congestion
, He
, tired
, fussy
, albuterol
Age
, Diagnosis
, Dosage
, Drug_Name
, Frequency
, Gender
, Lab_Name
, Lab_Result
, Symptom_Name
social_pipe = nlu.load('med_ner.jsl.enriched')
social_pipe.predict("The patient is a 21-day-old Caucasian male here for 2 days of congestion - mom has been suctioning yellow discharge from the patient's nares, plus she has noticed some mild problems with his breathing while feeding (but negative for any perioral cyanosis or retractions). One day ago, mom also noticed a tactile temperature and gave the patient Tylenol. Baby also has had some decreased p.o. intake. His normal breast-feeding is down from 20 minutes q.2h. to 5 to 10 minutes secondary to his respiratory congestion. He sleeps well, but has been more tired and has been fussy over the past 2 days. The parents noticed no improvement with albuterol treatments given in the ER. His urine output has also decreased; normally he has 8 to 10 wet and 5 dirty diapers per 24 hours, now he has down to 4 wet diapers per 24 hours. Mom denies any diarrhea. His bowel movements are yellow colored and soft in nature.")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | The patient is a 21-day-old Caucasian male her... | Caucasian | MISC | 0.5619 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The patient is a 21-day-old Caucasian male her... | Tylenol | ORG | 0.3466 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The patient is a 21-day-old Caucasian male her... | Baby | PER | 0.5074 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The patient is a 21-day-old Caucasian male her... | ER | LOC | 0.248 | [[-0.06767900288105011, 0.09451500326395035, -... |
0 | The patient is a 21-day-old Caucasian male her... | Mom | PER | 0.7925 | [[-0.06767900288105011, 0.09451500326395035, -... |
social_pipe.viz("The patient is a 21-day-old Caucasian male here for 2 days of congestion - mom has been suctioning yellow discharge from the patient's nares, plus she has noticed some mild problems with his breathing while feeding (but negative for any perioral cyanosis or retractions). One day ago, mom also noticed a tactile temperature and gave the patient Tylenol. Baby also has had some decreased p.o. intake. His normal breast-feeding is down from 20 minutes q.2h. to 5 to 10 minutes secondary to his respiratory congestion. He sleeps well, but has been more tired and has been fussy over the past 2 days. The parents noticed no improvement with albuterol treatments given in the ER. His urine output has also decreased; normally he has 8 to 10 wet and 5 dirty diapers per 24 hours, now he has down to 4 wet diapers per 24 hours. Mom denies any diarrhea. His bowel movements are yellow colored and soft in nature.")
28-year-old
, female
, gestational
, diabetes
, mellitus
, eight
, years
, prior
, type
, two
, diabetes
, mellitus
, T2DM
, HTG-induced
, pancreatitis
, three
, years
, prior
, acute
, hepatitis
, obesity
, body
, mass
, index
, BMI
, kg/m2
, polyuria
, polydipsia
, poor
, appetite
, vomiting
, Two
, weeks
, prior
, she
, five-day
, course
Injury_or_Poisoning
, Direction
, Test
, Admission_Discharge
, Death_Entity
, Relationship_Status
, Duration
, Respiration
, Hyperlipidemia
, Birth_Entity
, Age
, Labour_Delivery
, Family_History_Header
, BMI
, Temperature
, Alcohol
, Kidney_Disease
, Oncological
, Medical_History_Header
, Cerebrovascular_Disease
, Oxygen_Therapy
, O2_Saturation
, Psychological_Condition
, Heart_Disease
, Employment
, Obesity
, Disease_Syndrome_Disorder
, Pregnancy
, ImagingFindings
, Procedure
, Medical_Device
, Race_Ethnicity
, Section_Header
, Symptom
, Treatment
, Substance
, Route
, Drug_Ingredient
, Blood_Pressure
, Diet
, External_body_part_or_region
, LDL
, VS_Finding
, Allergen
, EKG_Findings
, Imaging_Technique
, Triglycerides
, RelativeTime
, Gender
, Pulse
, Social_History_Header
, Substance_Quantity
, Diabetes
, Modifier
, Internal_organ_or_component
, Clinical_Dept
, Form
, Drug_BrandName
, Strength
, Fetus_NewBorn
, RelativeDate
, Height
, Test_Result
, Sexually_Active_or_Sexual_Orientation
, Frequency
, Time
, Weight
, Vaccine
, Vital_Signs_Header
, Communicable_Disease
, Dosage
, Overweight
, Hypertension
, HDL
, Total_Cholesterol
, Smoking
, `clinical_pipe = nlu.load('med_ner.jsl.wip.clinical.modifier')
clinical_pipe.predict("HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-year-old white male veteran with multiple comorbidities, who has a history of bladder cancer diagnosed approximately two years ago by the VA Hospital. He underwent a resection there. He was to be admitted to the Day Hospital for cystectomy. He was seen in Urology Clinic and Radiology Clinic on 02/04/2003. HOSPITAL COURSE: Mr. Smith presented to the Day Hospital in anticipation for Urology surgery. On evaluation, EKG, echocardiogram was abnormal, a Cardiology consult was obtained. A cardiac adenosine stress MRI was then proceeded, same was positive for inducible ischemia, mild-to-moderate inferolateral subendocardial infarction with peri-infarct ischemia. In addition, inducible ischemia seen in the inferior lateral septum. Mr. Smith underwent a left heart catheterization, which revealed two vessel coronary artery disease. The RCA, proximal was 95% stenosed and the distal 80% stenosed. The mid LAD was 85% stenosed and the distal LAD was 85% stenosed. There was four Multi-Link Vision bare metal stents placed to decrease all four lesions to 0%. Following intervention, Mr. Smith was admitted to 7 Ardmore Tower under Cardiology Service under the direction of Dr. Hart. Mr. Smith had a noncomplicated post-intervention hospital course. He was stable for discharge home on 02/07/2003 with instructions to take Plavix daily for one month and Urology is aware of the same.")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | HISTORY OF PRESENT ILLNESS | ORG | 0.270525 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Smith | PER | 0.4312 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | VA Hospital | ORG | 0.47370002 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Day Hospital | ORG | 0.3237 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Urology Clinic and Radiology Clinic | ORG | 0.5485 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | HOSPITAL COURSE | MISC | 0.3839 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Smith | PER | 0.6266 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Day Hospital | ORG | 0.3542 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Urology | MISC | 0.2025 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Cardiology | MISC | 0.7151 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Smith | PER | 0.9256 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | RCA | ORG | 0.9264 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Multi-Link Vision | ORG | 0.47275 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Mr. Smith | PER | 0.46403334 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Ardmore Tower | LOC | 0.2574 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Cardiology Service | ORG | 0.55965 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Hart | PER | 0.4351 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Smith | PER | 0.9283 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Plavix | LOC | 0.2065 | [[0.4709100127220154, -0.29864001274108887, 0.... |
0 | HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-... | Urology | PER | 0.3635 | [[0.4709100127220154, -0.29864001274108887, 0.... |
clinical_pipe.viz("HISTORY OF PRESENT ILLNESS: Mr. Smith is a 60-year-old white male veteran with multiple comorbidities, who has a history of bladder cancer diagnosed approximately two years ago by the VA Hospital. He underwent a resection there. He was to be admitted to the Day Hospital for cystectomy. He was seen in Urology Clinic and Radiology Clinic on 02/04/2003. HOSPITAL COURSE: Mr. Smith presented to the Day Hospital in anticipation for Urology surgery. On evaluation, EKG, echocardiogram was abnormal, a Cardiology consult was obtained. A cardiac adenosine stress MRI was then proceeded, same was positive for inducible ischemia, mild-to-moderate inferolateral subendocardial infarction with peri-infarct ischemia. In addition, inducible ischemia seen in the inferior lateral septum. Mr. Smith underwent a left heart catheterization, which revealed two vessel coronary artery disease. The RCA, proximal was 95% stenosed and the distal 80% stenosed. The mid LAD was 85% stenosed and the distal LAD was 85% stenosed. There was four Multi-Link Vision bare metal stents placed to decrease all four lesions to 0%. Following intervention, Mr. Smith was admitted to 7 Ardmore Tower under Cardiology Service under the direction of Dr. Hart. Mr. Smith had a noncomplicated post-intervention hospital course. He was stable for discharge home on 02/07/2003 with instructions to take Plavix daily for one month and Urology is aware of the same.")
Description : Find general medical terms and medical entities.
Predicted Labes : Qualitative_Concept
, Organization
, Manufactured_Object
, Amino_Acid
, Peptide_or_Protein
, Pharmacologic_Substance
, Professional_or_Occupational_Group
, Cell_Component
, Neoplastic_Process
, Substance
, Laboratory_Procedure
, Nucleic_Acid_Nucleoside_or_Nucleotide
, Research_Activity
, Gene_or_Genome
, Indicator_Reagent_or_Diagnostic_Aid
, Biologic_Function
, Chemical
, Mammal
, Molecular_Function
, Quantitative_Concept
, Prokaryote
, Mental_or_Behavioral_Dysfunction
, Injury_or_Poisoning
, Body_Location_or_Region
, Spatial_Concept
, Nucleotide_Sequence
, Tissue
, Pathologic_Function
, Body_Substance
, Fungus
, Mental_Process
, Medical_Device
, Plant
, Health_Care_Activity
, Clinical_Attribute
, Genetic_Function
, Food
, Therapeutic_or_Preventive_Procedure
, Body_Part_Organ
, Organ_Component
, Geographic_Area
, Virus
, Biomedical_or_Dental_Material
, Diagnostic_Procedure
, Eukaryote
, Anatomical_Structure
, Organism_Attribute
, Molecular_Biology_Research_Technique
, Organic_Chemical
, Cell
, Daily_or_Recreational_Activity
, Population_Group
, Disease_or_Syndrome
, Group
, Sign_or_Symptom
, Body_System
clinical_pipe = nlu.load('med_ner.medmentions')
clinical_pipe.predict("Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Been taking Lipitor for 15 years , have experi... | Lipitor | MISC | 0.2087 | [[0.10356999933719635, -0.1432500034570694, -0... |
0 | Been taking Lipitor for 15 years , have experi... | Doctor | MISC | 0.6495 | [[0.10356999933719635, -0.1432500034570694, -0... |
clinical_pipe.viz("Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps")
Bilateral
, breast
, ultrasound
, ovoid mass
, 0.5 x 0.5 x 0.4
, cm
, anteromedial aspect
, left
, shoulder
, mass
, isoechoic echotexture
, muscle
, internal color flow
, benign fibrous tissue
, lipoma
ImagingTest
, Imaging_Technique
, ImagingFindings
, OtherFindings
, BodyPart
, Direction
, Test
, Symptom
, Disease_Syndrome_Disorder
, Medical_Device
, Procedure
, Measurements
, Units
clinical_pipe = nlu.load('med_ner.radiology.wip_clinical')
clinical_pipe.predict("""INTERPRETATION: There has been interval development of a moderate left-sided pneumothorax with near complete collapse of the left upper lobe. The lower lobe appears aerated. There is stable, diffuse, bilateral interstitial thickening with no definite acute air space consolidation. The heart and pulmonary vascularity are within normal limits. Left-sided port is seen with Groshong tip at the SVC/RA junction. No evidence for acute fracture, malalignment, or dislocation.""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | INTERPRETATION: There has been interval develo... | INTERPRETATION | MISC | 0.9615 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | The lower lobe | MISC | 0.51683336 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | The heart | LOC | 0.46095002 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | Groshong | LOC | 0.6005 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | SVC/RA | LOC | 0.408 | [[0.41714999079704285, -0.021769000217318535, ... |
clinical_pipe.viz("""INTERPRETATION: There has been interval development of a moderate left-sided pneumothorax with near complete collapse of the left upper lobe. The lower lobe appears aerated. There is stable, diffuse, bilateral interstitial thickening with no definite acute air space consolidation. The heart and pulmonary vascularity are within normal limits. Left-sided port is seen with Groshong tip at the SVC/RA junction. No evidence for acute fracture, malalignment, or dislocation.""")
Bilateral
, breast
, ultrasound
, ovoid mass
, 0.5 x 0.5 x 0.4
, cm
, anteromedial aspect
, left
, shoulder
, mass
, isoechoic echotexture
, muscle
, internal color flow
, benign fibrous tissue
, lipoma
Test_Result
, OtherFindings
, BodyPart
, ImagingFindings
, Disease_Syndrome_Disorder
, ImagingTest
, Measurements
, Procedure
, Score
, Test
, Medical_Device
, Direction
, Symptom
, Imaging_Technique
, ManualFix
, Units
clinical_pipe = nlu.load('med_ner.radiology.wip_greedy_biobert')
clinical_pipe.predict("Bilateral breast ultrasound was subsequently performed, which demonstrated an ovoid mass measuring approximately 0.5 x 0.5 x 0.4 cm in diameter located within the anteromedial aspect of the left shoulder. This mass demonstrates isoechoic echotexture to the adjacent muscle, with no evidence of internal color flow. This may represent benign fibrous tissue or a lipoma.")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | Bilateral breast ultrasound was subsequently p... | Bilateral | MISC | 0.6309 | [[-0.1833599954843521, -0.227960005402565, -0.... |
0 | Bilateral breast ultrasound was subsequently p... | This | LOC | 0.6025 | [[-0.1833599954843521, -0.227960005402565, -0.... |
clinical_pipe.viz("Bilateral breast ultrasound was subsequently performed, which demonstrated an ovoid mass measuring approximately 0.5 x 0.5 x 0.4 cm in diameter located within the anteromedial aspect of the left shoulder. This mass demonstrates isoechoic echotexture to the adjacent muscle, with no evidence of internal color flow. This may represent benign fibrous tissue or a lipoma.")
Kidney_Disease
, HDL
, Diet
, Test
, Imaging_Technique
, Triglycerides
, Obesity
, Duration
, Weight
, Social_History_Header
, ImagingTest
, Labour_Delivery
, Disease_Syndrome_Disorder
, Communicable_Disease
, Overweight
, Units
, Smoking
, Score
, Substance_Quantity
, Form
, Race_Ethnicity
, Modifier
, Hyperlipidemia
, ImagingFindings
, Psychological_Condition
, OtherFindings
, Cerebrovascular_Disease
, Date
, Test_Result
, VS_Finding
, Employment
, Death_Entity
, Gender
, Oncological
, Heart_Disease
, Medical_Device
, Total_Cholesterol
, ManualFix
, Time
, Route
, Pulse
, Admission_Discharge
, RelativeDate
, O2_Saturation
, Frequency
, RelativeTime
, Hypertension
, Alcohol
, Allergen
, Fetus_NewBorn
, Birth_Entity
, Age
, Respiration
, Medical_History_Header
, Oxygen_Therapy
, Section_Header
, LDL
, Treatment
, Vital_Signs_Header
, Direction
, BMI
, Pregnancy
, Sexually_Active_or_Sexual_Orientation
, Symptom
, Clinical_Dept
, Measurements
, Height
, Family_History_Header
, Substance
, Strength
, Injury_or_Poisoning
, Relationship_Status
, Blood_Pressure
, Drug
, Temperature,
EKG_Findings
, Diabetes
, BodyPart
, Vaccine
, Procedure
, Dosage
clinical_pipe = nlu.load('med_ner.jsl.wip.clinical.rd')
clinical_pipe.predict("""
INTERPRETATION: There has been interval development of a moderate left-sided pneumothorax with near complete collapse of the left upper lobe. The lower lobe appears aerated. There is stable, diffuse, bilateral interstitial thickening with no definite acute air space consolidation. The heart and pulmonary vascularity are within normal limits. Left-sided port is seen with Groshong tip at the SVC/RA junction. No evidence for acute fracture, malalignment, or dislocation.""")
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_wikiner_glove_840B_300 | entities_wikiner_glove_840B_300_class | entities_wikiner_glove_840B_300_confidence | word_embedding_glove | |
---|---|---|---|---|---|
0 | INTERPRETATION: There has been interval develo... | INTERPRETATION | MISC | 0.9615 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | The lower lobe | MISC | 0.51683336 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | The heart | LOC | 0.46095002 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | Groshong | LOC | 0.6005 | [[0.41714999079704285, -0.021769000217318535, ... |
0 | INTERPRETATION: There has been interval develo... | SVC/RA | LOC | 0.408 | [[0.41714999079704285, -0.021769000217318535, ... |
clinical_pipe.viz("""
INTERPRETATION: There has been interval development of a moderate left-sided pneumothorax with near complete collapse of the left upper lobe. The lower lobe appears aerated. There is stable, diffuse, bilateral interstitial thickening with no definite acute air space consolidation. The heart and pulmonary vascularity are within normal limits. Left-sided port is seen with Groshong tip at the SVC/RA junction. No evidence for acute fracture, malalignment, or dislocation.""")
Named Entities extracted by an NER model can be further classified into sub-classes or statuses, depending on the context of the sentence. See the following two examples :
headache
headache
headaches
All sentences have the entity headache
which is of class disease
.
But there is a semantic difference on what the actual status of the disease mentioned in text is. In the first and third sentence, Billy has no headache
, but in the second sentence Billy actually has a sentence
.
The Entity Assertion
Algorithms provided by JSL solve this problem. The disease
entity can be classified into ABSENT
for the first case and into PRESENT
for the second case. The third case can be classified into PRESENT IN FAMILY
.
This has immense implications for various data analytical approaches in the helathcare domain.
I.e. imagine you want you want to make a study about hearth attacks and survival rate of potential procedures. You can process all your digital patient notes with an Medical NER model and filter for documents that have the Hearth Attack
entity.
But your collected data will have wrong data entries because of the above mentioned Entity status problem. You cannot deduct that a document is talking about a patient having a hearth attack, unless you assert that the problem is actually there which is what the Resolutions algorithms do for you.
Keep in mind: This is a simplified example, entities should actually be mapped to their according Terminology (ICD-10-CM/ICD-10-PCS, etc..) to solve disambiguity problems and based on their codes all analysis should be performed
This algorithm is provided by Spark NLP for Healthcare's AssertionDLModel
Domain | Description | Spell | Predicted Entities | Examples | Reference Dataset |
---|---|---|---|---|---|
Radiology | Predict status of Radiology related entities | assert.radiology |
Confirmed , Negative , Suspected |
- Confirmed : X-Ray scan shows cancer in lung. - Negative : X-Ray scan shows no sign of cancer in lung. - Suspected :X-Ray raises suspicion of cancer in lung but does not confirm it. |
Internal Dataset by Annotated by John Snow Labs |
Healthcare/Clinical extended and Family JSL powerd | Predict status of, Healthcare/Clinical/Family related entities. Additional training with JSL Dataset | assert.jsl |
Present , Absent , Possible , Planned , Someoneelse , Past , Family , Hypotetical |
- Present : Patient diagnosed with cancer in 1999 - Absent : No sign of cancer was shown by the scans - Possible : Tests indicate patient might have cancer - Planned : CT-Scan is scheduled for 23.03.1999 - Someoneelse : The patient gave Aspirin to daugther. - Past : The patient has no more headaches since the operation - Family : The patients father has cancer . - Hypotetical :Death could be possible. |
2010 i2b2 + Data provided by JSL |
Healthcare/Clinical JSL powerd | Predict status of Healthcare/Clinical related entities. Additional training with JSL Dataset | assert.jsl_large |
present , absent , possible , planned , someoneelse , past |
- present : Patient diagnosed with cancer in 1999 - absent : No sign of cancer was shown by the scans - possible : Tests indicate patient might have cancer - planned : CT-Scan is scheduled for 23.03.1999 - someoneelse : The patient gave Aspirin to daugther - past : The patient has no more headaches since the operation |
2010 i2b2 + Data provided by JSL |
Healthcare/Clinical classic | Predict status of Healthcare/Clinical related entities | assert.biobert |
present , absent , possible , conditional , associated_with_someone_else ,hypothetical |
- present : Patient diagnosed with cancer in 1999 - absent : No sign of cancer was shown by the scans - possible : Tests indicate patient might have cancer - conditional If the test is positive, patient has AIDS - associated_with_someone_else : The patients father has cancer . - hypothetical :Death could be possible. |
2010 i2b2 |
# Restar Kernal and authorize again if RAM is full.
# You dont need to run this if you uploaded spark_nlp_for_healthcare.json
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
Confirmed
: X-Ray scan shows cancer
in lung. Negative
: X-Ray scan shows no sign of cancer
in lung. Suspected
:X-Ray raises suspicion
of cancer
in lung but does not confirm it.Confirmed
, Negative
, Suspected
model = nlu.load('en.med_ner.radiology assert.radiology')
model.predict('''
X-Ray scan shows cancer in lung.
X-Ray scan shows no sign of cancer in lung.
X-Ray raises suspicion of cancer in lung but does not confirm it.
''')
ner_radiology download started this may take some time. Approximate size to download 13.9 MB [OK!] assertion_dl_radiology download started this may take some time. Approximate size to download 1.3 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
assertion | document | entities_radiology | entities_radiology_class | entities_radiology_confidence | word_embedding_glove | |
---|---|---|---|---|---|---|
0 | Confirmed | X-Ray scan shows cancer in lung. X-Ray scan sh... | X-Ray scan | ImagingTest | 0.66865003 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Confirmed | X-Ray scan shows cancer in lung. X-Ray scan sh... | cancer | Disease_Syndrome_Disorder | 0.5239 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Confirmed | X-Ray scan shows cancer in lung. X-Ray scan sh... | lung | BodyPart | 0.9863 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Confirmed | X-Ray scan shows cancer in lung. X-Ray scan sh... | X-Ray scan | ImagingTest | 0.91945 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Negative | X-Ray scan shows cancer in lung. X-Ray scan sh... | cancer | Disease_Syndrome_Disorder | 0.9796 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Negative | X-Ray scan shows cancer in lung. X-Ray scan sh... | lung | BodyPart | 0.9784 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Suspected | X-Ray scan shows cancer in lung. X-Ray scan sh... | X-Ray | ImagingTest | 0.7777 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Suspected | X-Ray scan shows cancer in lung. X-Ray scan sh... | cancer | Disease_Syndrome_Disorder | 0.5654 | [[-0.04079213738441467, -0.14343440532684326, ... |
0 | Suspected | X-Ray scan shows cancer in lung. X-Ray scan sh... | lung | BodyPart | 0.745 | [[-0.04079213738441467, -0.14343440532684326, ... |
model.viz('''
X-Ray scan shows cancer in lung.
X-Ray scan shows no sign of cancer in lung.
X-Ray raises suspicion of cancer in lung but does not confirm it.
''')
Present
: Patient diagnosed with cancer
in 1999 Absent
: No sign of cancer
was shown by the scans Possible
: Tests indicate patient might have cancer
Planned
: CT-Scan
is scheduled for 23.03.1999 Someoneelse
: The patient gave Aspirin
to daugther. Past
: The patient has no more headaches
since the operation Family
: The patients father has cancer
. Hypotetical
:Death
could be possible.Present
, Absent
, Possible
, Planned
, Someoneelse
, Past
, Family
, Hypotetical
model = nlu.load('en.med_ner.clinical assert.jsl')
model.predict("""
- Patient diagnosed with cancer in 1999
- No sign of cancer was shown by the scans
- Tests indicate patient might have cancer
- CT-Scan is scheduled for 23.03.1999
- The patient gave Aspirin to daugther.
- The patient has no more headaches since the operation
- The patients father has cancer.
- Death could be possible.
""")
ner_clinical download started this may take some time. Approximate size to download 13.9 MB [OK!] assertion_jsl download started this may take some time. Approximate size to download 1.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
assertion | document | entities_clinical | entities_clinical_class | entities_clinical_confidence | word_embedding_glove | |
---|---|---|---|---|---|---|
0 | Possible | - Patient diagnosed with cancer in 1999 - No s... | cancer | PROBLEM | 0.901 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Absent | - Patient diagnosed with cancer in 1999 - No s... | cancer | PROBLEM | 0.9971 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Absent | - Patient diagnosed with cancer in 1999 - No s... | the scans | TEST | 0.7327 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Hypothetical | - Patient diagnosed with cancer in 1999 - No s... | cancer | PROBLEM | 0.9962 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Hypothetical | - Patient diagnosed with cancer in 1999 - No s... | CT-Scan | TEST | 0.9999 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Hypothetical | - Patient diagnosed with cancer in 1999 - No s... | Aspirin | TREATMENT | 0.5154 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Absent | - Patient diagnosed with cancer in 1999 - No s... | more headaches | PROBLEM | 0.97445 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Hypothetical | - Patient diagnosed with cancer in 1999 - No s... | the operation | TREATMENT | 0.9537 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
0 | Possible | - Patient diagnosed with cancer in 1999 - No s... | cancer | PROBLEM | 1.0 | [[0.09684590995311737, 0.0810248926281929, 0.0... |
model.viz("""
Patient diagnosed with cancer in 1999.
No sign of cancer was shown by the scans.
Tests indicate patient might have cancer.
CT-Scan is scheduled for 23.03.1999.
The patient leg was amputated last year.
The patients father has cancer.
Cancer is still possible for the patient.
""")
present
: Patient diagnosed with cancer
in 1999 absent
: No sign of cancer
was shown by the scans possible
: Tests indicate patient might have cancer
planned
: CT-Scan
is scheduled for 23.03.1999 someoneelse
: The patient gave Aspirin
to daugther past
: The patient has no more headaches
since the operationpresent
, absent
, possible
, planned
, someoneelse
, past
model = nlu.load('en.med_ner.clinical assert.jsl_large')
model.predict("""
Patient diagnosed with cancer in 1999.
No sign of cancer was shown by the scans.
Tests indicate patient might have cancer.
CT-Scan is scheduled for 23.03.1999.
The patient gave Aspirin to daugther.
The patient has no more headaches since the operation.
""")
ner_clinical download started this may take some time. Approximate size to download 13.9 MB [OK!] assertion_jsl_large download started this may take some time. Approximate size to download 1.3 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
assertion | document | entities_clinical | entities_clinical_class | entities_clinical_confidence | word_embedding_glove | |
---|---|---|---|---|---|---|
0 | present | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 0.9999 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | absent | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 0.9999 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | absent | Patient diagnosed with cancer in 1999. No sign... | the scans | TEST | 0.99825 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | hypothetical | Patient diagnosed with cancer in 1999. No sign... | Tests | TEST | 0.9926 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | possible | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 1.0 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | planned | Patient diagnosed with cancer in 1999. No sign... | CT-Scan | TEST | 0.8754 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | planned | Patient diagnosed with cancer in 1999. No sign... | Aspirin | TREATMENT | 0.9994 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | absent | Patient diagnosed with cancer in 1999. No sign... | more headaches | PROBLEM | 0.89695 | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | present | Patient diagnosed with cancer in 1999. No sign... | the operation | TREATMENT | 0.71575 | [[-0.08453157544136047, 0.20632991194725037, -... |
model.viz("""
Patient diagnosed with cancer in 1999.
No sign of cancer was shown by the scans.
Tests indicate patient might have cancer.
CT-Scan is scheduled for 23.03.1999.
The patient leg was amputated last year.
The patients father has cancer.
Cancer is still possible for the patient.
""")
present
: Patient diagnosed with cancer
in 1999 absent
: No sign of cancer
was shown by the scans possible
: Tests indicate patient might have cancer
conditional
If the test is positive, patient has AIDS
associated_with_someone_else
: The patients father has cancer
. hypothetical
:Death
could be possible.present
, absent
, possible
, conditional
, associated_with_someone_else
,hypothetical
model = nlu.load('en.med_ner.clinical assert.biobert')
model.predict("""
Patient diagnosed with cancer in 1999.
No sign of cancer was shown by the scans.
Patients X-Ray indicate possiblity of cancer.
CT-Scan is scheduled for 23.03.1999.
The patient leg was amputated last year.
If the test is positive, patient has AIDS
Cancer is still possible for the patient.
""")
ner_clinical download started this may take some time. Approximate size to download 13.9 MB [OK!] assertion_dl_biobert download started this may take some time. Approximate size to download 3 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] biobert_pubmed_base_cased download started this may take some time. Approximate size to download 386.4 MB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
assertion | document | entities_clinical | entities_clinical_class | entities_clinical_confidence | word_embedding_biobert | word_embedding_glove | |
---|---|---|---|---|---|---|---|
0 | present | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 0.9999 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | absent | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 0.9999 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | absent | Patient diagnosed with cancer in 1999. No sign... | the scans | TEST | 0.99825 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | present | Patient diagnosed with cancer in 1999. No sign... | Patients X-Ray | TEST | 0.8908 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | possible | Patient diagnosed with cancer in 1999. No sign... | cancer | PROBLEM | 1.0 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | present | Patient diagnosed with cancer in 1999. No sign... | CT-Scan | TEST | 0.8754 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | present | Patient diagnosed with cancer in 1999. No sign... | amputated | TREATMENT | 0.9996 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | present | Patient diagnosed with cancer in 1999. No sign... | the test | TEST | 0.7149 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | possible | Patient diagnosed with cancer in 1999. No sign... | positive | PROBLEM | 0.9998 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | hypothetical | Patient diagnosed with cancer in 1999. No sign... | AIDS Cancer | PROBLEM | 0.9972 | [[-0.2633698880672455, 0.2661483883857727, 0.4... | [[-0.08453157544136047, 0.20632991194725037, -... |
model.viz("""
Patient diagnosed with cancer in 1999.
No sign of cancer was shown by the scans.
Patients X-Ray indicate possiblity of cancer.
CT-Scan is scheduled for 23.03.1999.
The patient leg was amputated last year.
If the test is positive, patient has AIDS
Cancer is still possible for the patient.
""")
data = '''A . Record date : 2093-01-13 , David Hale , M.D . , Name : Hendrickson , Ora MR .
# 7194334 Date : 01/13/93 PCP : Oliveira , 25 years-old , Record date : 2079-11-09 . Cocke County Baptist Hospital . 0295 Keats Street'''
res = nlu.load("med_ner.jsl.wip.clinical en.de_identify").predict(data)
res.de_identified.values
ner_wikiner_glove_840B_300 download started this may take some time. Approximate size to download 14.8 MB [OK!] deidentify_rb download started this may take some time. Approximate size to download 3.8 KB [OK!] glove_840B_300 download started this may take some time. Approximate size to download 2.3 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
array(['A . <ORG> date : <DATE> , <PER> , <MISC> , <PER> . # <ID> Date : <DATE> PCP :'], dtype=object)
Most sentences and documents have a lof of entities
which can be extracted with NER. These entities alone already provide a lot of insight and information about your data, but there is even more information extractable...
Each entity
in a sentence always has some kind of relationship
to every other entity
in the sentence. In other words, each entity pair has a relationship ! If a sentence has N entities, there are NxN
potential binary relationships and NxNxK
for k-ary relationships
.
The RelationExtraction
Algortihms provided by JSL classify for each pair of entities what the type of relationship between is, based on some domain.
A concrete use-case example:
Lets say you want to analyze the survival rate of amputation procedures
peformed on the left hand
.
Using just NER
, we could find all documents that mention the entity amputation
, left
and hand
.
The collected data will have wrong entries, imagine the following clinical note :
left
foot
and his right
hand
were amputated
This record would be part of our analysis, if we just use NER
with the above mentioned filtering.
The RelationExtraction
Algorithms provided by JSL solves this problem. The relation.bodypart.directions
model can classify for each entity pair, wether they are related or not.
In our example, it can classify that left
and foot
are related and that right
and hand
are related. Based on these classified relationships, we can easily enhance our filters and make sure no wrong records are used for our surival rate analysis.
But what about the following sentence?
left
hand
was saved but his foot
was amputated
This would pass all the NER
and Relationship
filters defined sofar. But we can easily cover this case by using the relation.bodypart.procedures
model, which can predict wether a procedure entity was peformed on some bodypart or not. In the last example, it can predict foot
and amputated
are related, buthand
and amputated
are not in relationship, aswell as left
and amputated
(since every entity pair gets a prediction).
In conclusion, we can adjust our filters to additionaly verify that the amputation
procedure is peformed on a hand
and that this hand
is in relationship with a direction entity with the value left
.
Keep in mind: This is a simplified example, entities should actually be mapped to their according Terminology (ICD-10-CM/ICD-10-PCS, etc..) to solve disambiguity problems and based on their codes all analysis should be performed
These algorithm are provided by Spark NLP for Healthcare's RelationExtraction and RelationExtractionDL
Domain | Description | Sample NLU Spells | Predictable Relationships and Explanation |
---|---|---|---|
Dates and Clinical Entities | Predict binary temporal relationship between Date Entities and Clinical Entities |
relation.date |
- 1 for Date Entity and Clinical Entity are related. - 0 for Date Entity and Clinical Entity are not related |
Body Parts and Directions | Predict binary direction relationship between Bodypart Entities and Direction Entities |
relation.bodypart.direction |
- 1 for Body Part and Direction are related - 0 for Body Part and Direction are not related |
Body Parts and Problems | Predict binary location relationship between Bodypart Entities and Problem Entities |
relation.bodypart.problem |
- 1 for Body Part and Problem are related - 0 for Body Part and Problem are not related |
Body Parts and Procedures | Predict binary application relationship between Bodypart Entities and Procedure Entities |
relation.bodypart.procedure |
- 1 for Body Part and Test/Procedure are related - 0 for Body Part and Test/Procedure are not related |
Adverse Effects between drugs (ADE) | Predict binary effect relationship between Drugs Entities and Adverse Effects/Problem Entities |
relation.ade |
- 1 for Adverse Event Entity and Drug are related - 0 for Adverse Event Entity and Drug are not related |
Phenotype abnormalities,Genes and Diseases | Predict binary caused by relationship between Phenotype Abnormality Entities , Gene Entities and Disease Entities |
relation.humen_phenotype_gene |
- 1 for Gene Entity and Phenotype Entity are related - 0 for Gene Entity and Phenotype Entity are not related |
Temporal events | Predict multi-class temporal relationship between Time Entities and Event Entities |
relation.temporal_events |
- AFTER if Any Entity occured after Another Entity - BEFORE if Any Entity occured before Another Entity - OVERLAP if Any Entity during Another Entity |
Dates and Tests/Results | Predict multi-class temporal cause,reasoning and conclusion relationship between Date Entities , Test Entities and Result Entities |
relation.test_result_date |
- relation.test_result_date - is_finding_of for Medical Entity is found because of Test Entity - is_result_of for Medical Entity reason for doing Test Entity - is_date_of for Date Entity relates to time of Test/Result - 0 : No relationship |
Clinical Problem, Treatment and Tests | Predict multi-class cause,reasoning and effect relationship between Treatment Entities , Problem Entities and Test Entities |
relation.clinical |
- TrIP : A certain treatment has improved/cured a medical problem - TrWP : A patient's medical problem has deteriorated or worsened because of treatment - TrCP : A treatment caused a medical problem - TrAP : A treatment administered for a medical problem - TrNAP : The administration of a treatment was avoided because of a medical problem - TeRP : A test has revealed some medical problem - TeCP : A test was performed to investigate a medical problem - PIP : Two problems are related to each other |
DDI Effects of using Multiple Drugs (Drug Drug Interaction) | Predict multi-class effects, mechanisms and reasoning for DDI effects(Drug Drug Interaction) relationships between Drug Entities |
relation.drug_drug_interaction |
- DDI-advise when an advice/recommendation regarding aDrug Entity and Drug Entity is given - DDI-effect when Drug Entity and Drug Entity have an effect on the human body (pharmacodynamic mechanism). Including a clinical finding, signs or symptoms, an increased toxicity or therapeutic failure. - DDI-int when effect between Drug Entity and Drug Entity is already known and thus provides no additional information. - DDI-mechanism when Drug Entity and Drug Entity are affected by an organism (pharmacokinetic). Such as the changes in levels or concentration in a drug. Used for DDIs that are described by their PK mechanism - DDI-false when a Drug Entity and Drug Entity have no interaction mentioned in the text. |
Posology (Drugs, Dosage, Duration, Frequency,Strength) | Predict multi-class posology relationships between Drug Entities ,Dosage Entities ,Strength Entities ,Route Entities , Form Entities , Duration Entities and Frequency Entities |
relation.posology |
- DRUG-ADE if Problem Entity Adverse effect of Drug Entity - DRUG-DOSAGE if Dosage Entity refers to a Drug Entity - DRUG-DURATION if Duration Entity refers to a Drug Entity - DRUG-FORM if Mode/Form Entity refers to intake form of Drug Entity - DRUG-FREQUENCY if Frequency Entity refers to usage of Drug Entity - DRUG-REASON if Problem Entity is reason for taking Drug Entity - DRUG-ROUTE if Route Entity refer to administration method of Drug Entity - DRUG-STRENGTH if Strength Entity refers to Drug Entity |
Chemicals and Proteins | Predict Regulator, Upregulator, Downregulator, Agonist, Antagonist, Modulator, Cofactor, Substrate relationships between Chemical Entities and Protein Entities |
relation.chemprot |
- CPR:1 if One ChemProt Entity is Part of of Another ChemProt Entity - CPR:2 if One ChemProt Entity is Regulator (Direct or Indirect) of Another ChemProt Entity - CPR:3 if One ChemProt Entity is Upregulator/Activator/Indirect Upregulator of Another ChemProt Entity - CPR:4 if One ChemProt Entity is Downregulator/Inhibitor/Indirect Downregulator of Another ChemProt Entity - CPR:5 if One ChemProt Entity is Agonist of Another ChemProt Entity - CPR:6 if One ChemProt Entity is Antagonist of Another ChemProt Entity - CPR:7 if One ChemProt Entity is Modulator (Activator/Inhibitor) of Another ChemProt Entity - CPR:8 if One ChemProt Entity is Cofactor of Another ChemProt Entity - CPR:9 if One ChemProt Entity is Substrate and product of of Another ChemProt Entity - CPR:10 if One ChemProt Entity is Not Related to Another ChemProt Entity |
Domain | Sentence With Relationships | Predicted Relationships for Sample Sentence | Reference Links |
---|---|---|---|
Dates and Clinical Entities | This 73 y/o patient had CT on 1/12/95 , with cognitive decline since 8/11/94 . |
- 1 for CT and1/12/95 - 0 for cognitive decline and 1/12/95 - 1 for cognitive decline and 8/11/94 |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Directions | MRI demonstrated infarction in the upper - brain stem , left cerebellum and right basil ganglia |
- 1 for uppper and brain stem - 0 for upper and cerebellum - 1 for left and cerebellum |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Problems | Patient reported numbness in his left hand and bleeding from ear . |
- 1 for numbness and hand - 0 for numbness and ear - 1 for bleeding and ear |
Internal Dataset by Annotated by John Snow Labs |
Body Parts and Procedures | The chest was scanned with portable ultrasound and amputation was performed on foot |
- 1 for chest and portable ultrasound - 0 for chest and amputation - 1 for foot and amputation |
Internal Dataset by Annotated by John Snow Labs |
Adverse Effects between drugs (ADE) | Taking Lipitor for 15 years, experienced much sever fatigue ! Doctor moved me to voltaren 2 months ago , so far only experienced cramps |
- 1 for sever fatigue and Liptor - 0 for sever fatigue and voltaren - 0 for cramps and Liptor - 1 for cramps and voltaren |
Internal Dataset by Annotated by John Snow Labs |
Phenotype abnormalities,Genes and Diseases | She has a retinal degeneration , hearing loss and renal failure , short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive. |
- 1 for hearing loss and SH3PXD2B - 0 for retinal degeneration and hearing loss - 1 for retinal degeneration and autosomal recessive |
PGR aclAntology |
Temporal events | She is diagnosed with cancer in 1991 . Then she was admitted to Mayo Clinic in May 2000 and discharged in October 2001 |
- OVERLAP for cancer and 1991 - AFTER for additted and Mayo Clinic - BEFORE for admitted and discharged |
Temporal JSL Dataset and n2c2 |
Dates and Tests/Results | On 23 March 1995 a X-Ray applied to patient because of headache , found tumor in brain |
- is_finding_of for tumor and X-Ray - is_result_of for headache and X-Ray - is_date_of for 23 March 1995 and X-Ray |
Internal Dataset by Annotated by John Snow Labs |
Clinical Problem, Treatment and Tests | - TrIP : infection resolved with antibiotic course - TrWP : the tumor was growing despite the drain - TrCP : penicillin causes a rash - TrAP :Dexamphetamine for narcolepsy - TrNAP : Ralafen was not given because of ulcers - TeRP : an echocardiogram revealed a pericardial effusion - TeCP : chest x-ray for pneumonia - PIP : Azotemia presumed secondary to sepsis |
- TrIP for infection and antibiotic course - TrWP for tumor and drain - TrCP for penicillin andrash - TrAP for Dexamphetamine and narcolepsy - TrNAP for Ralafen and ulcers - TeRP for echocardiogram and pericardial effusion - TeCP for chest x-ray and pneumonia - PIP for Azotemia and sepsis |
2010 i2b2 relation challenge |
DDI Effects of using Multiple Drugs (Drug Drug Interaction) | - DDI-advise : UROXATRAL should not be used in combination with other alpha-blockers - DDI-effect : Chlorthalidone may potentiate the action of other antihypertensive drugs - DDI-int : The interaction of omeprazole and ketoconazole has been established - DDI-mechanism : Grepafloxacin may inhibit the metabolism of theobromine - DDI-false : Aspirin does not interact with Chlorthalidone |
- DDI-advise for UROXATRAL and alpha-blockers - DDI-effect for Chlorthalidone and antihypertensive drugs - DDI-int for omeprazole and ketoconazole - DDI-mechanism for Grepafloxacin and theobromine - DDI-false for Aspirin and Chlorthalidone |
DDI Extraction corpus |
Posology (Drugs, Dosage, Duration, Frequency,Strength) | - DRUG-ADE : had a headache after taking Paracetamol - DRUG-DOSAGE : took 0.5ML ofCelstone - DRUG-DURATION : took Aspirin daily for two weeks - DRUG-FORM : took Aspirin as tablets - DRUG-FREQUENCY : Aspirin usage is weekly - DRUG-REASON : Took Aspirin because of headache - DRUG-ROUTE : Aspirin taken orally - DRUG-STRENGTH : 2mg of Aspirin |
- DRUG-ADE for headache and Paracetamol - DRUG-DOSAGE for 0.5ML and Celstone - DRUG-DURATION for Aspirin and for two weeks - DRUG-FORM for Aspirin and tablets - DRUG-FREQUENCY for Aspirin and weekly - DRUG-REASON for Aspirin and headache - DRUG-ROUTE for Aspirin and orally - DRUG-STRENGTH for 2mg and Aspirin |
Magge, Scotch, Gonzalez-Hernandez (2018) |
Chemicals and Proteins | - CPR:1 (Part of) : The amino acid sequence of the rabbit alpha(2A)-adrenoceptor has many interesting properties. - CPR:2 (Regulator) : Triacsin inhibited ACS activity - CPR:3 (Upregulator) : Ibandronate increases the expression of the FAS gene - CPR:4 (Downregulator) : Vitamin C treatment resulted in reduced C-Rel nuclear translocation - CPR:5 (Agonist) : Reports show tricyclic antidepressants act as agnonists at distinct opioid receptors - CPR:6 (Antagonist) : GDC-0152 is a drug triggers tumor cell apoptosis by selectively antagonizing LAPs - CPR:7 (Modulator) : Hydrogen sulfide is a allosteric modulator of ATP-sensitive potassium channels - CPR:8 (Cofactor) : polyinosinic:polycytidylic acid and the IFNα/β demonstrate capability of endogenous IFN. - CPR:9 (Substrate) : ZIP9 plays an important role in the transport and toxicity of Cd(2+) cells - CPR:10 (Not Related) : Studies indicate that GSK-3β inhibition by palinurin cannot be competed out by ATP |
- CPR:1 (Part of) for amino acid and rabbit alpha(2A)-adrenoceptor - CPR:2 (Regulator) for Triacsin and ACS - CPR:3 (Upregulator) for Ibandronate and FAS gene - CPR:4 (Downregulator) for Vitamin C and C-Rel - CPR:5 (Agonist) for tricyclic antidepressants and opioid receptors - CPR:6 (Antagonist) (Antagonist) for GDC-0152 and LAPs - CPR:7 (Modulator) for Hydrogen sulfide and ATP-sensitive potassium channels - CPR:8 (Cofactor) for polyinosinic:polycytidylic acid and IFNα/β - CPR:9 (Substrate) for ZIP9 and Cd(2+) cells - CPR:10 (Not Related) for GSK-3β and ATP |
ChemProt Paper |
# Restar Kernal and authorize again if RAM is full.
# You dont need to run this if you uploaded spark_nlp_for_healthcare.json
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
Date Entities
and Clinical Entities
CT
on 1/12/95
, with cognitive decline
since 8/11/94
.1
for CT
and1/12/95
0
for cognitive decline
and 1/12/95
1
for cognitive decline
and 8/11/94
1
for Date Entity
and Clinical Entity
are related. 0
for Date Entity
and Clinical Entity
are not relatedmodel = nlu.load('en.med_ner.jsl.wip.clinical.greedy relation.date')
model.predict(' Patient developed cancer after a mercury poisoning in 1/12/95. Since 4/11/21 patient showed signs of Leukemia')
jsl_ner_wip_greedy_clinical download started this may take some time. Approximate size to download 14.5 MB [OK!] redl_date_clinical_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_jsl | entities_jsl_class | entities_jsl_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | Patient developed cancer after a mercury poiso... | [cancer, mercury poisoning, 1/12/95, 4/11/21, ... | [Oncological, Disease_Syndrome_Disorder, Date,... | [0.9963, 0.2891, 1.0, 0.9995, 0.1211] | 1 | 0.99989593 | cancer | Oncological | mercury poisoning | Disease_Syndrome_Disorder | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient developed cancer after a mercury poiso... | [cancer, mercury poisoning, 1/12/95, 4/11/21, ... | [Oncological, Disease_Syndrome_Disorder, Date,... | [0.9963, 0.2891, 1.0, 0.9995, 0.1211] | 1 | 0.99986863 | cancer | Oncological | 1/12/95 | Date | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient developed cancer after a mercury poiso... | [cancer, mercury poisoning, 1/12/95, 4/11/21, ... | [Oncological, Disease_Syndrome_Disorder, Date,... | [0.9963, 0.2891, 1.0, 0.9995, 0.1211] | 1 | 0.9999012 | mercury poisoning | Disease_Syndrome_Disorder | 1/12/95 | Date | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient developed cancer after a mercury poiso... | [cancer, mercury poisoning, 1/12/95, 4/11/21, ... | [Oncological, Disease_Syndrome_Disorder, Date,... | [0.9963, 0.2891, 1.0, 0.9995, 0.1211] | 1 | 0.9998129 | 4/11/21 | Date | Leukemia | Oncological | [[-0.08453157544136047, 0.20632991194725037, -... |
model.viz('Patient developed cancer after a mercury poisoning in 1/12/95. Since 4/11/21 patient showed signs of Leukemia')
Bodypart Entities
and Direction Entities
MRI
demonstrated infarction in the upper
- brain stem
, left
cerebellum
and right
basil ganglia
1
for uppper
and brain stem
0
for upper
and cerebellum
1
for left
and cerebellum
1
for Body Part
and Direction
are related 0
for Body Part
and Direction
are not related model = nlu.load('en.med_ner.jsl.wip.clinical.greedy relation.bodypart.direction')
model.predict('Patients left foot was amputated. The right foot and the right arm were saved.')
jsl_ner_wip_greedy_clinical download started this may take some time. Approximate size to download 14.5 MB [OK!] redl_bodypart_direction_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_jsl | entities_jsl_class | entities_jsl_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 1 | 0.99991226 | left | Direction | foot | External_body_part_or_region | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 1 | 0.99994993 | right | Direction | foot | External_body_part_or_region | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 0 | 0.98365545 | right | Direction | right | Direction | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 0 | 0.94846493 | right | Direction | arm | External_body_part_or_region | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 0 | 0.97780734 | foot | External_body_part_or_region | right | Direction | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 0 | 0.98036677 | foot | External_body_part_or_region | arm | External_body_part_or_region | [[-0.22872048616409302, 0.13868580758571625, -... |
0 | Patients left foot was amputated. The right fo... | [left, foot, right, foot, right, arm] | [Direction, External_body_part_or_region, Dire... | [0.3165, 0.9057, 0.8216, 0.7721, 0.9319, 0.3967] | 1 | 0.9999397 | right | Direction | arm | External_body_part_or_region | [[-0.22872048616409302, 0.13868580758571625, -... |
model.viz('Patients left foot was amputated. The right foot and the right arm were saved.')
Bodypart Entities
and Problem Entities
numbness
in his left hand
and bleeding
from ear
.1
for numbness
and hand
0
for numbness
and ear
1
for bleeding
and ear
1
for Body Part
and Problem
are related 0
for Body Part
and Problem
are not related model = nlu.load('en.med_ner.jsl.wip.clinical.greedy relation.bodypart.problem')
model.predict('Patient reported numbness in left hand. Also reported pain in the shoulder')
jsl_ner_wip_greedy_clinical download started this may take some time. Approximate size to download 14.5 MB [OK!] redl_bodypart_problem_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_jsl | entities_jsl_class | entities_jsl_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | Patient reported numbness in left hand. Also r... | [numbness, left, hand, pain, shoulder] | [Symptom, Direction, External_body_part_or_reg... | [0.538, 0.6695, 0.2217, 0.8378, 0.0964] | 1 | 0.9997179 | numbness | Symptom | left | Direction | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient reported numbness in left hand. Also r... | [numbness, left, hand, pain, shoulder] | [Symptom, Direction, External_body_part_or_reg... | [0.538, 0.6695, 0.2217, 0.8378, 0.0964] | 1 | 0.9999393 | numbness | Symptom | hand | External_body_part_or_region | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient reported numbness in left hand. Also r... | [numbness, left, hand, pain, shoulder] | [Symptom, Direction, External_body_part_or_reg... | [0.538, 0.6695, 0.2217, 0.8378, 0.0964] | 1 | 0.9991986 | left | Direction | hand | External_body_part_or_region | [[-0.08453157544136047, 0.20632991194725037, -... |
0 | Patient reported numbness in left hand. Also r... | [numbness, left, hand, pain, shoulder] | [Symptom, Direction, External_body_part_or_reg... | [0.538, 0.6695, 0.2217, 0.8378, 0.0964] | 1 | 0.9998549 | pain | Symptom | shoulder | External_body_part_or_region | [[-0.08453157544136047, 0.20632991194725037, -... |
model.viz('Patient reported numbness in left hand. Also reported pain in the shoulder')
Bodypart Entities
and Procedure Entities
chest
was scanned with portable ultrasound
and amputation
was performed on foot
1
for chest
and portable ultrasound
0
for chest
and amputation
1
for foot
and amputation
1
for Body Part
and Test/Procedure
are related 0
for Body Part
and Test/Procedure
are not related model = nlu.load('en.med_ner.jsl.wip.clinical.greedy relation.bodypart.procedure')
model.predict('The chest was scanned with portable ultrasound. Amputation was performed on foot')
jsl_ner_wip_greedy_clinical download started this may take some time. Approximate size to download 14.5 MB [OK!] redl_bodypart_procedure_test_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_jsl | entities_jsl_class | entities_jsl_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | The chest was scanned with portable ultrasound... | [chest, portable ultrasound, Amputation, foot] | [External_body_part_or_region, Test, Procedure... | [0.954, 0.306, 0.9979, 0.0588] | 1 | 0.9980913 | chest | External_body_part_or_region | portable ultrasound | Test | [[-0.0823686420917511, -0.3178570866584778, 0.... |
0 | The chest was scanned with portable ultrasound... | [chest, portable ultrasound, Amputation, foot] | [External_body_part_or_region, Test, Procedure... | [0.954, 0.306, 0.9979, 0.0588] | 1 | 0.92126226 | Amputation | Procedure | foot | External_body_part_or_region | [[-0.0823686420917511, -0.3178570866584778, 0.... |
model.viz('The chest was scanned with portable ultrasound. Amputation was performed on foot')
Drugs Entities
and Adverse Effects/Problem Entities
Lipitor
for 15 years, experienced much sever fatigue
! Doctor moved me to voltaren
2 months ago , so far only experienced cramps
1
for sever fatigue
and Liptor
0
for sever fatigue
and voltaren
0
for cramps
and Liptor
1
for cramps
and voltaren
1
for Adverse Event Entity
and Drug
are related 0
for Adverse Event Entity
and Drug
are not relatedmodel = nlu.load('en.med_ner.ade.clinical relation.ade')
model.predict('Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps')
ner_ade_clinical download started this may take some time. Approximate size to download 13.9 MB [OK!] redl_ade_biobert download started this may take some time. Approximate size to download 383.3 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_ade | entities_ade_class | entities_ade_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | Been taking Lipitor for 15 years , have experi... | [Lipitor, severe fatigue, voltaren, cramps] | [DRUG, ADE, DRUG, ADE] | [0.9969, 0.57505, 0.9907, 0.9609] | 1 | 0.99785197 | Lipitor | DRUG | severe fatigue | ADE | [[0.2214706838130951, 0.12367766350507736, 0.0... |
0 | Been taking Lipitor for 15 years , have experi... | [Lipitor, severe fatigue, voltaren, cramps] | [DRUG, ADE, DRUG, ADE] | [0.9969, 0.57505, 0.9907, 0.9609] | 1 | 0.9978865 | voltaren | DRUG | cramps | ADE | [[0.2214706838130951, 0.12367766350507736, 0.0... |
model.viz('Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps')
Phenotype Abnormality Entities
, Gene Entities
and Disease Entities
retinal degeneration
, hearing loss
and renal failure
, short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive.1
for hearing loss
and SH3PXD2B
0
for retinal degeneration
and hearing loss
1
for retinal degeneration
and autosomal recessive
1
for Gene Entity
and Phenotype Entity
are related 0
for Gene Entity
and Phenotype Entity
are not relatedmodel = nlu.load('en.med_ner.human_phenotype.gene_clinical relation.humen_phenotype_gene')
model.predict('She has a retinal degeneration and hearing loss caused by \
Mutations in the SH3PXD2B gene coding for the Tks4 protein ')
ner_human_phenotype_gene_clinical download started this may take some time. Approximate size to download 14 MB [OK!] redl_human_phenotype_gene_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_human_phenotype | entities_human_phenotype_class | entities_human_phenotype_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | She has a retinal degeneration and hearing los... | [retinal degeneration, hearing loss, SH3PXD2B] | [HP, HP, GENE] | [0.85940003, 0.8434, 1.0] | 0 | 0.8636064 | retinal degeneration | HP | hearing loss | HP | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She has a retinal degeneration and hearing los... | [retinal degeneration, hearing loss, SH3PXD2B] | [HP, HP, GENE] | [0.85940003, 0.8434, 1.0] | 1 | 0.5719643 | retinal degeneration | HP | SH3PXD2B | GENE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She has a retinal degeneration and hearing los... | [retinal degeneration, hearing loss, SH3PXD2B] | [HP, HP, GENE] | [0.85940003, 0.8434, 1.0] | 1 | 0.7213649 | hearing loss | HP | SH3PXD2B | GENE | [[-0.21964989602565765, -0.2844458520412445, -... |
model.viz('She has a retinal degeneration and hearing loss caused by \
Mutations in the SH3PXD2B gene coding for the Tks4 protein ')
WARNING: pip is being invoked by an old script wrapper. This will fail in a future version of pip. Please see https://github.com/pypa/pip/issues/5599 for advice on fixing the underlying issue. To avoid this problem you can invoke Python with '-m pip' instead of running pip directly.
Collecting spark-nlp-display Downloading spark_nlp_display-1.9.1-py3-none-any.whl (95 kB) Requirement already satisfied: numpy in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (1.21.5) Requirement already satisfied: spark-nlp in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (3.4.2) Requirement already satisfied: pandas in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (1.3.5) Collecting svgwrite==1.4 Downloading svgwrite-1.4-py3-none-any.whl (66 kB) Requirement already satisfied: ipython in /usr/local/lib/python3.7/dist-packages (from spark-nlp-display) (5.5.0) Requirement already satisfied: pickleshare in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (0.7.5) Requirement already satisfied: traitlets>=4.2 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (5.1.1) Requirement already satisfied: pygments in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (2.6.1) Requirement already satisfied: simplegeneric>0.8 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (0.8.1) Requirement already satisfied: decorator in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (4.4.2) Requirement already satisfied: setuptools>=18.5 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (57.4.0) Requirement already satisfied: pexpect in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (4.8.0) Requirement already satisfied: prompt-toolkit<2.0.0,>=1.0.4 in /usr/local/lib/python3.7/dist-packages (from ipython->spark-nlp-display) (1.0.18) Requirement already satisfied: wcwidth in /usr/local/lib/python3.7/dist-packages (from prompt-toolkit<2.0.0,>=1.0.4->ipython->spark-nlp-display) (0.2.5) Requirement already satisfied: six>=1.9.0 in /usr/local/lib/python3.7/dist-packages (from prompt-toolkit<2.0.0,>=1.0.4->ipython->spark-nlp-display) (1.15.0) Requirement already satisfied: python-dateutil>=2.7.3 in /usr/local/lib/python3.7/dist-packages (from pandas->spark-nlp-display) (2.8.2) Requirement already satisfied: pytz>=2017.3 in /usr/local/lib/python3.7/dist-packages (from pandas->spark-nlp-display) (2018.9) Requirement already satisfied: ptyprocess>=0.5 in /usr/local/lib/python3.7/dist-packages (from pexpect->ipython->spark-nlp-display) (0.7.0) Installing collected packages: svgwrite, spark-nlp-display Successfully installed spark-nlp-display-1.9.1 svgwrite-1.4
Time Entities
and Event Entities
cancer
in 1991
. Then she was admitted to Mayo Clinic
in May 2000 and discharged
in October 2001OVERLAP
for cancer
and 1991
AFTER
for additted
and Mayo Clinic
BEFORE
for admitted
and discharged
AFTER
if Any Entity
occured after Another Entity
BEFORE
if Any Entity
occured before Another Entity
OVERLAP
if Any Entity
during Another Entity
model = nlu.load('en.med_ner.events_clinical relation.temporal_events')
model.predict('She is diagnosed with cancer in 1991. Then she was admitted to Mayo Clinic in May 2000 and discharged in October 2001')
ner_events_clinical download started this may take some time. Approximate size to download 13.8 MB [OK!] redl_temporal_events_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_events_clinical | entities_events_clinical_class | entities_events_clinical_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | BEFORE | 0.76975965 | diagnosed | OCCURRENCE | cancer | PROBLEM | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | OVERLAP | 0.7382456 | cancer | PROBLEM | 1991 | DATE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | AFTER | 0.86001897 | admitted | OCCURRENCE | Mayo Clinic | CLINICAL_DEPT | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | BEFORE | 0.5504242 | admitted | OCCURRENCE | discharged | OCCURRENCE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | OVERLAP | 0.8135876 | Mayo Clinic | CLINICAL_DEPT | May 2000 | DATE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | BEFORE | 0.54912627 | Mayo Clinic | CLINICAL_DEPT | discharged | OCCURRENCE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | OVERLAP | 0.534672 | Mayo Clinic | CLINICAL_DEPT | October 2001 | DATE | [[-0.21964989602565765, -0.2844458520412445, -... |
0 | She is diagnosed with cancer in 1991. Then she... | [diagnosed, cancer, 1991, admitted, Mayo Clini... | [OCCURRENCE, PROBLEM, DATE, OCCURRENCE, CLINIC... | [0.9921, 0.9954, 0.9929, 0.9903, 0.68544996, 0... | OVERLAP | 0.7216446 | May 2000 | DATE | October 2001 | DATE | [[-0.21964989602565765, -0.2844458520412445, -... |
model.viz('She was diagnosed with cancer in 1991. Then she was admitted to Mayo Clinic in May 2000 and discharged in October 2001')
Date Entities
, Test Entities
and Result Entities
23 March 1995
a X-Ray
applied to patient because of headache
, found tumor
in brainis_finding_of
for tumor
and X-Ray
is_result_of
for headache
and X-Ray
is_date_of
for 23 March 1995
and X-Ray
relation.test_result_date
is_finding_of
for Medical Entity
is found because of Test Entity
is_result_of
for Medical Entity
reason for doing Test Entity
is_date_of
for Date Entity
relates to time of Test/Result
0
: No relationshipmodel = nlu.load('en.med_ner.jsl.wip.clinical relation.test_result_date')
model.predict('On 23 March 1995 a X-Ray applied to patient because of headache, found tumor in brain')
jsl_ner_wip_clinical download started this may take some time. Approximate size to download 14.5 MB [OK!] re_test_result_date download started this may take some time. Approximate size to download 9.3 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] dependency_conllu download started this may take some time. Approximate size to download 16.7 MB [OK!] pos_anc download started this may take some time. Approximate size to download 3.9 MB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_jsl | entities_jsl_class | entities_jsl_confidence | labeled_dependency | pos | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove_clinical | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | is_date_of | 0.99999106 | 23 March 1995 | Date | X-Ray | Test | [[-0.08693569153547287, -0.0026769430842250586... |
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | is_date_of | 0.9999976 | 23 March 1995 | Date | headache | Symptom | [[-0.08693569153547287, -0.0026769430842250586... |
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | is_date_of | 0.9999995 | 23 March 1995 | Date | tumor in brain | Oncological | [[-0.08693569153547287, -0.0026769430842250586... |
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | O | 0.5060819 | X-Ray | Test | headache | Symptom | [[-0.08693569153547287, -0.0026769430842250586... |
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | is_finding_of | 0.5808518 | X-Ray | Test | tumor in brain | Oncological | [[-0.08693569153547287, -0.0026769430842250586... |
0 | On 23 March 1995 a X-Ray applied to patient be... | [23 March 1995, X-Ray, headache, tumor in brain] | [Date, Test, Symptom, Oncological] | [0.71573335, 0.3999, 0.3996, 0.3104] | [March, March, ROOT, March, applied, applied, ... | [IN, CD, NNP, CD, DT, NNP, VBD, TO, NN, IN, IN... | O | 0.93679327 | headache | Symptom | tumor in brain | Oncological | [[-0.08693569153547287, -0.0026769430842250586... |
model.viz('On 23 March 1995 a X-Ray applied to patient because of headache, found tumor in brain', viz_type='relation')
Treatment Entities
, Problem Entities
and Test Entities
TrIP
: infection
resolved with antibiotic course
TrWP
: the tumor
was growing despite the drain
TrCP
: penicillin
causes a rash
TrAP
:Dexamphetamine
for narcolepsy
TrNAP
: Ralafen
was not given because of ulcers
TeRP
: an echocardiogram
revealed a pericardial effusion
TeCP
: chest x-ray
for pneumonia
PIP
: Azotemia
presumed secondary to sepsis
TrIP
for infection
and antibiotic course
TrWP
for tumor
and drain
TrCP
for penicillin
andrash
TrAP
for Dexamphetamine
and narcolepsy
TrNAP
for Ralafen
and ulcers
TeRP
for echocardiogram
and pericardial effusion
TeCP
for chest x-ray
and pneumonia
PIP
for Azotemia
and sepsis
TrIP
: A certain treatment has improved/cured a medical problem TrWP
: A patient's medical problem has deteriorated or worsened because of treatment TrCP
: A treatment caused a medical problem TrAP
: A treatment administered for a medical problem TrNAP
: The administration of a treatment was avoided because of a medical problem TeRP
: A test has revealed some medical problem TeCP
: A test was performed to investigate a medical problem PIP
: Two problems are related to each othermodel = nlu.load('en.med_ner.clinical relation.clinical')
model.predict("""A 28-year-old female with a history of gestational diabetes mellitus diagnosed eight years prior to presentation and subsequent type two diabetes mellitus ( T2DM ),
one prior episode of HTG-induced pancreatitis three years prior to presentation, associated with an acute hepatitis , and obesity with a body mass index ( BMI ) of 33.5 kg/m2 , presented with a one-week history of polyuria , polydipsia , poor appetite , and vomiting . Two weeks prior to presentation , she was treated with a five-day course of amoxicillin for a respiratory tract infection . She was on metformin , glipizide , and dapagliflozin for T2DM and atorvastatin and gemfibrozil for HTG . She had been on dapagliflozin for six months at the time of presentation. Physical examination on presentation was significant for dry oral mucosa ; significantly , her abdominal examination was benign with no tenderness , guarding , or rigidity . Pertinent laboratory findings on admission were : serum glucose 111 mg/dl , bicarbonate 18 mmol/l , anion gap 20 , creatinine 0.4 mg/dL , triglycerides 508 mg/dL , total cholesterol 122 mg/dL , glycated hemoglobin ( HbA1c ) 10% , and venous pH 7.27 . Serum lipase was normal at 43 U/L . Serum acetone levels could not be assessed as blood samples kept hemolyzing due to significant lipemia . The patient was initially admitted for starvation ketosis , as she reported poor oral intake for three days prior to admission . However , serum chemistry obtained six hours after presentation revealed her glucose was 186 mg/dL , the anion gap was still elevated at 21 , serum bicarbonate was 16 mmol/L , triglyceride level peaked at 2050 mg/dL , and lipase was 52 U/L . The β-hydroxybutyrate level was obtained and found to be elevated at 5.29 mmol/L - the original sample was centrifuged and the chylomicron layer removed prior to analysis due to interference from turbidity caused by lipemia again . The patient was treated with an insulin drip for euDKA and HTG with a reduction in the anion gap to 13 and triglycerides to 1400 mg/dL , within 24 hours . Her euDKA was thought to be precipitated by her respiratory tract infection in the setting of SGLT2 inhibitor use . The patient was seen by the endocrinology service and she was discharged on 40 units of insulin glargine at night , 12 units of insulin lispro with meals , and metformin 1000 mg two times a day . It was determined that all SGLT2 inhibitors should be discontinued indefinitely .
She had close follow-up with endocrinology post discharge .
""")
ner_clinical download started this may take some time. Approximate size to download 13.9 MB [OK!] redl_clinical_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_clinical | entities_clinical_class | entities_clinical_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | O | 0.7702896 | gestational diabetes mellitus | PROBLEM | subsequent type two diabetes mellitus | PROBLEM | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | PIP | 0.8335136 | gestational diabetes mellitus | PROBLEM | T2DM | PROBLEM | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | PIP | 0.7316658 | gestational diabetes mellitus | PROBLEM | HTG-induced pancreatitis | PROBLEM | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | PIP | 0.84107006 | gestational diabetes mellitus | PROBLEM | an acute hepatitis | PROBLEM | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | PIP | 0.7376963 | gestational diabetes mellitus | PROBLEM | obesity | PROBLEM | [[0.040217556059360504, 0.4003961980342865, 0.... |
... | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | O | 0.9777103 | the anion gap | TEST | triglycerides | TEST | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | TrCP | 0.9878628 | her respiratory tract infection | PROBLEM | SGLT2 inhibitor | TREATMENT | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | O | 0.9996606 | insulin glargine | TREATMENT | insulin lispro | TREATMENT | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | O | 0.9999064 | insulin glargine | TREATMENT | metformin | TREATMENT | [[0.040217556059360504, 0.4003961980342865, 0.... |
0 | A 28-year-old female with a history of gestati... | [gestational diabetes mellitus, subsequent typ... | [PROBLEM, PROBLEM, PROBLEM, PROBLEM, PROBLEM, ... | [0.8904333, 0.78448, 0.9992, 0.99745, 0.981733... | O | 0.99992347 | insulin lispro | TREATMENT | metformin | TREATMENT | [[0.040217556059360504, 0.4003961980342865, 0.... |
201 rows × 11 columns
# - TrIP: A certain treatment has improved/cured a medical problem
# - TrWP: A patient's medical problem has deteriorated or worsened because of treatment
# - TrCP: A treatment caused a medical problem
# - TrAP: A treatment administered for a medical problem
# - TrNAP: The administration of a treatment was avoided because of a medical problem
# - TeRP: A test has revealed some medical problem
# - TeCP: A test was performed to investigate a medical problem
# - PIP: Two problems are related to each other
model.viz("""
infection resolved with antibiotic course.
the tumor was growing despite the drain.
penicillin causes a rash.
Dexamphetamine for narcolepsy.
Ralafen was not given because of ulcers.
an echocardiogram revealed a pericardial effusion.
chest x-ray for pneumonia.
Azotemia presumed secondary to sepsis.
""", viz_type='relation'
)
model.viz("""A 28-year-old female with a history of gestational diabetes mellitus diagnosed eight years prior to presentation and subsequent type two diabetes mellitus ( T2DM ),
one prior episode of HTG-induced pancreatitis three years prior to presentation, associated with an acute hepatitis , and obesity with a body mass index ( BMI ) of 33.5 kg/m2 , presented with a one-week history of polyuria , polydipsia , poor appetite , and vomiting . Two weeks prior to presentation , she was treated with a five-day course of amoxicillin for a respiratory tract infection . She was on metformin , glipizide , and dapagliflozin for T2DM and atorvastatin and gemfibrozil for HTG . She had been on dapagliflozin for six months at the time of presentation. Physical examination on presentation was significant for dry oral mucosa ; significantly , her abdominal examination was benign with no tenderness , guarding , or rigidity . Pertinent laboratory findings on admission were : serum glucose 111 mg/dl , bicarbonate 18 mmol/l , anion gap 20 , creatinine 0.4 mg/dL , triglycerides 508 mg/dL , total cholesterol 122 mg/dL , glycated hemoglobin ( HbA1c ) 10% , and venous pH 7.27 . Serum lipase was normal at 43 U/L . Serum acetone levels could not be assessed as blood samples kept hemolyzing due to significant lipemia . The patient was initially admitted for starvation ketosis , as she reported poor oral intake for three days prior to admission . However , serum chemistry obtained six hours after presentation revealed her glucose was 186 mg/dL , the anion gap was still elevated at 21 , serum bicarbonate was 16 mmol/L , triglyceride level peaked at 2050 mg/dL , and lipase was 52 U/L . The β-hydroxybutyrate level was obtained and found to be elevated at 5.29 mmol/L - the original sample was centrifuged and the chylomicron layer removed prior to analysis due to interference from turbidity caused by lipemia again . The patient was treated with an insulin drip for euDKA and HTG with a reduction in the anion gap to 13 and triglycerides to 1400 mg/dL , within 24 hours . Her euDKA was thought to be precipitated by her respiratory tract infection in the setting of SGLT2 inhibitor use . The patient was seen by the endocrinology service and she was discharged on 40 units of insulin glargine at night , 12 units of insulin lispro with meals , and metformin 1000 mg two times a day . It was determined that all SGLT2 inhibitors should be discontinued indefinitely .
She had close follow-up with endocrinology post discharge .
""")
Drug Entities
DDI-advise
: UROXATRAL
should not be used in combination with other alpha-blockers
DDI-effect
: Chlorthalidone
may potentiate the action of other antihypertensive drugs
DDI-int
: The interaction of omeprazole
and ketoconazole
has been established DDI-mechanism
: Grepafloxacin
may inhibit the metabolism of theobromine
DDI-false
: Aspirin
does not interact with Chlorthalidone
DDI-advise
for UROXATRAL
and alpha-blockers
DDI-effect
for Chlorthalidone
and antihypertensive drugs
DDI-int
for omeprazole
and ketoconazole
DDI-mechanism
for Grepafloxacin
and theobromine
DDI-false
for Aspirin
and Chlorthalidone
DDI-advise
when an advice/recommendation regarding aDrug Entity
and Drug Entity
is given DDI-effect
when Drug Entity
and Drug Entity
have an effect on the human body (pharmacodynamic mechanism). Including a clinical finding, signs or symptoms, an increased toxicity or therapeutic failure. DDI-int
when effect between Drug Entity
and Drug Entity
is already known and thus provides no additional information. DDI-mechanism
when Drug Entity
and Drug Entity
are affected by an organism (pharmacokinetic). Such as the changes in levels or concentration in a drug. Used for DDIs that are described by their PK mechanism DDI-false
when a Drug Entity
and Drug Entity
have no interaction mentioned in the text.model = nlu.load('en.med_ner.posology relation.drug_drug_interaction')
model.predict("""When carbamazepine is withdrawn from the combination therapy, aripiprazole dose should then be reduced. \
If additional adrenergic drugs are to be administered by any route, \
they should be used with caution because the pharmacologically predictable sympathetic effects of Metformin may be potentiated"""
)
ner_posology download started this may take some time. Approximate size to download 13.8 MB [OK!] redl_drug_drug_interaction_biobert download started this may take some time. Approximate size to download 383.4 MB [OK!] embeddings_clinical download started this may take some time. Approximate size to download 1.6 GB [OK!] sentence_detector_dl download started this may take some time. Approximate size to download 354.6 KB [OK!]
document | entities_posology | entities_posology_class | entities_posology_confidence | relation_relation | relation_relation_confidence | relation_relation_entity1 | relation_relation_entity1_class | relation_relation_entity2 | relation_relation_entity2_class | word_embedding_glove | |
---|---|---|---|---|---|---|---|---|---|---|---|
0 | When carbamazepine is withdrawn from the combi... | [carbamazepine, aripiprazole, adrenergic drugs... | [DRUG, DRUG, DRUG, DRUG] | [0.5977, 0.995, 0.676, 0.9998] | DDI-false | 0.94385505 | carbamazepine | DRUG | aripiprazole | DRUG | [[-0.06080734729766846, -0.2955009639263153, -... |
0 | When carbamazepine is withdrawn from the combi... | [carbamazepine, aripiprazole, adrenergic drugs... | [DRUG, DRUG, DRUG, DRUG] | [0.5977, 0.995, 0.676, 0.9998] | DDI-effect | 0.5874562 | adrenergic drugs | DRUG | Metformin | DRUG | [[-0.06080734729766846, -0.2955009639263153, -... |
# - DDI-advise when an advice/recommendation regarding aDrug Entity and Drug Entity is given
# - DDI-effect when Drug Entity and Drug Entity have an effect on the human body (pharmacodynamic mechanism). Including a clinical finding, signs or symptoms, an increased toxicity or therapeutic failure.
# - DDI-int when effect between Drug Entity and Drug Entity is already known and thus provides no additional information.
# - DDI-mechanism when Drug Entity and Drug Entity are affected by an organism (pharmacokinetic). Such as the changes in levels or concentration in a drug. Used for DDIs that are described by their PK mechanism
# - DDI-false when a Drug Entity and Drug Entity have no interaction mentioned in the text.
model.viz("""
Aspirin should be used in combination with Paracetamol.
Xanax potentiates the action of other antihypertensive drugs.
Strong interaction of Liptor and Ambien has been established.
Grepafloxacin may inhibit the metabolism of theobromine.
Avastin does not interact with Chlorthalidone.
"""
)
Drug Entities
,Dosage Entities
,Strength Entities
,Route Entities
, Form Entities
, Duration Entities
and Frequency Entities
DRUG-ADE
: had a headache
after taking Paracetamol
DRUG-DOSAGE
: took 0.5ML
ofCelstone
DRUG-DURATION
: took Aspirin
daily for two weeks
DRUG-FORM
: took Aspirin
as tablets
DRUG-FREQUENCY
: Aspirin
usage is weekly
DRUG-REASON
: Took Aspirin
because of headache
DRUG-ROUTE
: Aspirin
taken orally
DRUG-STRENGTH
: 2mg
of Aspirin
DRUG-ADE
for headache
and Paracetamol
DRUG-DOSAGE
for 0.5ML
and Celstone
DRUG-DURATION
for Aspirin
and for two weeks
DRUG-FORM
for Aspirin
and tablets
DRUG-FREQUENCY
for Aspirin
and weekly
DRUG-REASON
for Aspirin
and headache
DRUG-ROUTE
for Aspirin
and orally
DRUG-STRENGTH
for 2mg
and Aspirin
DRUG-ADE
if Problem Entity
Adverse effect of Drug Entity
DRUG-DOSAGE
if Dosage Entity
refers to a Drug Entity
DRUG-DURATION
if Duration Entity
refers to a Drug Entity
DRUG-FORM
if Mode/Form Entity
refers to intake form of Drug Entity
DRUG-FREQUENCY
if Frequency Entity
refers to usage of Drug Entity
DRUG-REASON
if Problem Entity
is reason for taking Drug Entity
DRUG-ROUTE
if Route Entity
refer to administration method of Drug Entity
DRUG-STRENGTH
if Strength Entity
refers to Drug Entity
model = nlu.load('en.med_ner.posology.large relation.posology')
model.predict("""Patient is given Fragmin 5000 units subcutaneously daily, Xenaderm to wounds topically b.i.d., Lantus 40 units subcutaneously at bedtime,
OxyContin 30 mg p.o. q.12 h., folic acid 1 mg daily, levothyroxine 0.1 mg p.o. daily, Prevacid 30 mg daily, Avandia 4 mg daily, Norvasc 10 mg daily,
Lexapro 20 mg daily, aspirin 81 mg daily, Senna 2 tablets p.o. q.a.m., Neurontin 400 mg p.o. t.i.d., Percocet 5/325 mg 2 tablets q.4 h. p.r.n.,
magnesium citrate 1 bottle p.o. p.r.n., sliding scale coverage insulin, Wellbutrin 100 mg p.o. daily, and Bactrim DS b.i.d.""")
ner_posology_large download started this may take some time. Approximate size to download 13.8 MB [OK!]
--------------------------------------------------------------------------- KeyError Traceback (most recent call last) /usr/local/lib/python3.7/dist-packages/nlu/__init__.py in load(request, path, verbose, gpu, streamlit_caching) 95 continue ---> 96 nlu_component = nlu_ref_to_component(nlu_ref) 97 # if we get a list of components, then the NLU reference is a pipeline, we do not need to check order /usr/local/lib/python3.7/dist-packages/nlu/pipe/component_resolution.py in nlu_ref_to_component(nlu_ref, detect_lang, authenticated) 155 else: --> 156 resolved_component = get_trained_component_for_nlp_model_ref(lang, nlu_ref, nlp_ref, license_type, model_params) 157 /usr/local/lib/python3.7/dist-packages/nlu/pipe/component_resolution.py in get_trained_component_for_nlp_model_ref(lang, nlu_ref, nlp_ref, license_type, model_configs) 218 model_configs: Optional[Dict[str, any]] = None) -> NluComponent: --> 219 anno_class = Spellbook.nlp_ref_to_anno_class[nlp_ref] 220 component = anno_class_to_empty_component(anno_class) KeyError: None During handling of the above exception, another exception occurred: Exception Traceback (most recent call last) <ipython-input-13-ab106e744d4d> in <module>() ----> 1 model = nlu.load('en.med_ner.posology.large relation.posology') 2 model.predict("""Patient is given Fragmin 5000 units subcutaneously daily, Xenaderm to wounds topically b.i.d., Lantus 40 units subcutaneously at bedtime, 3 OxyContin 30 mg p.o. q.12 h., folic acid 1 mg daily, levothyroxine 0.1 mg p.o. daily, Prevacid 30 mg daily, Avandia 4 mg daily, Norvasc 10 mg daily, 4 Lexapro 20 mg daily, aspirin 81 mg daily, Senna 2 tablets p.o. q.a.m., Neurontin 400 mg p.o. t.i.d., Percocet 5/325 mg 2 tablets q.4 h. p.r.n., 5 magnesium citrate 1 bottle p.o. p.r.n., sliding scale coverage insulin, Wellbutrin 100 mg p.o. daily, and Bactrim DS b.i.d.""") /usr/local/lib/python3.7/dist-packages/nlu/__init__.py in load(request, path, verbose, gpu, streamlit_caching) 109 print(err) 110 raise Exception( --> 111 f"Something went wrong during creating the Spark NLP model for your request = {request} Did you use a NLU Spell?") 112 # Complete Spark NLP Pipeline, which is defined as a DAG given by the starting Annotators 113 try: Exception: Something went wrong during creating the Spark NLP model for your request = en.med_ner.posology.large relation.posology Did you use a NLU Spell?
# - DRUG-DOSAGE: took 0.5ML ofCelstone.
# - DRUG-DURATION: took Aspirin daily for two weeks.
# - DRUG-FORM: took Aspirin as tablets.
# - DRUG-FREQUENCY : Aspirin usage is weekly.
# - DRUG-REASON : Took Aspirin because pain.
# - DRUG-ROUTE: Aspirin taken orally.
# - DRUG-STRENGTH: 2mg of Aspirin.
model.viz("""
took 0.5ML ofCelstone.
took Aspirin daily for two weeks.
took Aspirin as tablets.
Aspirin usage is weekly.
Took Aspirin because pain.
Aspirin taken orally.
2mg of Aspirin.
""", viz_type='relation')
model.viz("""Patient is given Fragmin 5000 units subcutaneously daily, Xenaderm to wounds topically b.i.d., Lantus 40 units subcutaneously at bedtime,
OxyContin 30 mg p.o. q.12 h., folic acid 1 mg daily, levothyroxine 0.1 mg p.o. daily, Prevacid 30 mg daily, Avandia 4 mg daily, Norvasc 10 mg daily,
Lexapro 20 mg daily, aspirin 81 mg daily, Senna 2 tablets p.o. q.a.m., Neurontin 400 mg p.o. t.i.d., Percocet 5/325 mg 2 tablets q.4 h. p.r.n.,
magnesium citrate 1 bottle p.o. p.r.n., sliding scale coverage insulin, Wellbutrin 100 mg p.o. daily, and Bactrim DS b.i.d.""", viz_type='relation')
Chemical Entities
and Protein Entities
CPR:1 (Part of)
: The amino acid
sequence of the rabbit alpha(2A)-adrenoceptor
has many interesting properties. CPR:2 (Regulator)
: Triacsin
inhibited ACS
activity CPR:3 (Upregulator)
: Ibandronate
increases the expression of the FAS gene
CPR:4 (Downregulator)
: Vitamin C
treatment resulted in reduced C-Rel
nuclear translocation CPR:5 (Agonist)
: Reports show tricyclic antidepressants
act as agnonists at distinct opioid receptors
CPR:6 (Antagonist)
: GDC-0152
is a drug triggers tumor cell apoptosis by selectively antagonizing LAPs
CPR:7 (Modulator)
: Hydrogen sulfide
is a allosteric modulator of ATP-sensitive potassium channels
CPR:8 (Cofactor)
: Using polyinosinic:polycytidylic acid
and the IFNα/β
we demonstrate the capability of endogenous IFN to promote the expression of CXCL10. CPR:9 (Substrate)
: ZIP9
plays an important role in the transport and toxicity of Cd(2+) cells
CPR:10 (Not Related)
: Studies indicate that GSK-3β
inhibition by palinurin cannot be competed out by ATP
CPR:1 (Part of)
for amino acid
and rabbit alpha(2A)-adrenoceptor
CPR:2 (Regulator)
for Triacsin
and ACS
CPR:3 (Upregulator)
for Ibandronate
and FAS gene
CPR:4 (Downregulator)
for Vitamin C
and C-Rel
CPR:5 (Agonist)
for tricyclic antidepressants
and opioid receptors
CPR:6 (Antagonist) (Antagonist)
for GDC-0152
and LAPs
CPR:7 (Modulator)
for Hydrogen sulfide
and ATP-sensitive potassium channels
CPR:8 (Cofactor)
for polyinosinic:polycytidylic acid
and IFNα/β
CPR:9 (Substrate)
for ZIP9
and Cd(2+) cells
CPR:10 (Not Related)
for GSK-3β
and ATP
CPR:1
if One ChemProt Entity
is Part of
of Another ChemProt Entity
CPR:2
if One ChemProt Entity
is Regulator (Direct or Indirect)
of Another ChemProt Entity
CPR:3
if One ChemProt Entity
is Upregulator/Activator/Indirect Upregulator
of Another ChemProt Entity
CPR:4
if One ChemProt Entity
is Downregulator/Inhibitor/Indirect Downregulator
of Another ChemProt Entity
CPR:5
if One ChemProt Entity
is Agonist
of Another ChemProt Entity
CPR:6
if One ChemProt Entity
is Antagonist
of Another ChemProt Entity
CPR:7
if One ChemProt Entity
is Modulator (Activator/Inhibitor)
of Another ChemProt Entity
CPR:8
if One ChemProt Entity
is Cofactor
of Another ChemProt Entity
CPR:9
if One ChemProt Entity
is Substrate and product of
of Another ChemProt Entity
CPR:10
if One ChemProt Entity
is Not Related
to Another ChemProt Entity
model = nlu.load('med_ner.chemprot.clinical relation.chemprot')
model.predict('In this study, we examined the effects of mitiglinide on various cloned K(ATP) channels (Kir6.2/SUR1, Kir6.2/SUR2A, and Kir6.2/SUR2B) reconstituted in COS-1 cells, and compared them to another meglitinide-related compound, nateglinide. Patch-clamp analysis using inside-out recording configuration showed that mitiglinide inhibits the Kir6.2/SUR1 channel currents in a dose-dependent manner (IC50 value, 100 nM) but does not significantly inhibit either Kir6.2/SUR2A or Kir6.2/SUR2B channel currents even at high doses (more than 10 microM). Nateglinide inhibits Kir6.2/SUR1 and Kir6.2/SUR2B channels at 100 nM, and inhibits Kir6.2/SUR2A channels at high concentrations (1 microM). Binding experiments on mitiglinide, nateglinide, and repaglinide to SUR1 expressed in COS-1 cells revealed that they inhibit the binding of [3H]glibenclamide to SUR1 (IC50 values: mitiglinide, 280 nM; nateglinide, 8 microM; repaglinide, 1.6 microM), suggesting that they all share a glibenclamide binding site. The insulin responses to glucose, mitiglinide, tolbutamide, and glibenclamide in MIN6 cells after chronic mitiglinide, nateglinide, or repaglinide treatment were comparable to those after chronic tolbutamide and glibenclamide treatment. These results indicate that, similar to the sulfonylureas, mitiglinide is highly specific to the Kir6.2/SUR1 complex, i.e., the pancreatic beta-cell K(ATP) channel, and suggest that mitiglinide may be a clinically useful anti-diabetic drug.')
# - CPR:1 (Part of) The amino acid sequence of the rabbit alpha(2A)-adrenoceptor has many interesting properties.
# - CPR:2 (Regulator) Triacsin inhibited ACS activity.
# - CPR:3 (Upregulator) Ibandronate increases the expression of the FAS gene.
# - CPR:4 (Downregulator) Vitamin C treatment resulted in reduced C-Rel nuclear translocation.
# - CPR:5 (Agonist) Reports show tricyclic antidepressants act as agnonists at distinct opioid receptors.
# - CPR:6 (Antagonist) GDC-0152 is a drug triggers tumor cell apoptosis by selectively antagonizing LAPs.
# - CPR:7 (Modulator) Hydrogen sulfide is a allosteric modulator of ATP-sensitive potassium channels.
# - CPR:8 (Cofactor) Using polyinosinic:polycytidylic acid and the IFNα/β we demonstrate the capability of endogenous IFN to promote the expression of CXCL10.
# - CPR:9 (Substrate) ZIP9 plays an important role in the transport and toxicity of Cd(2+) cells.
# - CPR:10 (Not Related) Studies indicate that GSK-3β inhibition by palinurin cannot be competed out by ATP.
model.viz("""
The amino acid sequence of the rabbit alpha(2A)-adrenoceptor has many interesting properties.
Triacsin inhibited ACS activity.
Ibandronate increases the expression of the FAS gene.
Vitamin C treatment resulted in reduced C-Rel nuclear translocation.
Reports show tricyclic antidepressants act as agnonists at distinct opioid receptors.
GDC-0152 is a drug triggers tumor cell apoptosis by selectively antagonizing LAPs.
Hydrogen sulfide is a allosteric modulator of ATP-sensitive potassium channels.
Using polyinosinic:polycytidylic acid and the IFNα/β we demonstrate the capability of endogenous IFN to promote the expression of CXCL10.
ZIP9 plays an important role in the transport and toxicity of Cd(2+) cells.
Studies indicate that GSK-3β inhibition by palinurin cannot be competed out by ATP.
"""
)
model.viz('In this study, we examined the effects of mitiglinide on various cloned K(ATP) channels (Kir6.2/SUR1, Kir6.2/SUR2A, and Kir6.2/SUR2B) reconstituted in COS-1 cells, and compared them to another meglitinide-related compound, nateglinide. Patch-clamp analysis using inside-out recording configuration showed that mitiglinide inhibits the Kir6.2/SUR1 channel currents in a dose-dependent manner (IC50 value, 100 nM) but does not significantly inhibit either Kir6.2/SUR2A or Kir6.2/SUR2B channel currents even at high doses (more than 10 microM). Nateglinide inhibits Kir6.2/SUR1 and Kir6.2/SUR2B channels at 100 nM, and inhibits Kir6.2/SUR2A channels at high concentrations (1 microM). Binding experiments on mitiglinide, nateglinide, and repaglinide to SUR1 expressed in COS-1 cells revealed that they inhibit the binding of [3H]glibenclamide to SUR1 (IC50 values: mitiglinide, 280 nM; nateglinide, 8 microM; repaglinide, 1.6 microM), suggesting that they all share a glibenclamide binding site. The insulin responses to glucose, mitiglinide, tolbutamide, and glibenclamide in MIN6 cells after chronic mitiglinide, nateglinide, or repaglinide treatment were comparable to those after chronic tolbutamide and glibenclamide treatment. These results indicate that, similar to the sulfonylureas, mitiglinide is highly specific to the Kir6.2/SUR1 complex, i.e., the pancreatic beta-cell K(ATP) channel, and suggest that mitiglinide may be a clinically useful anti-diabetic drug.')
# Restar Kernal and authorize again if RAM is full.
# You dont need to run this if you uploaded spark_nlp_for_healthcare.json
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
clinical_pipe = nlu.load('med_ner.medmentions')
clinical_pipe
clinical_pipe.predict("This is an 82 - year-old male with a history of prior tobacco use , hypertension , chronic renal insufficiency , COPD , gastritis , and TIA who initially presented to Braintree with a non-ST elevation MI and Guaiac positive stools , transferred to St . Margaret\'s Center for Women & Infants for cardiac catheterization with PTCA to mid LAD lesion complicated by hypotension and bradycardia requiring Atropine , IV fluids and transient dopamine possibly secondary to vagal reaction , subsequently transferred to CCU for close monitoring , hemodynamically stable at the time of admission to the CCU .")
Named entities are sub-strings in a text that can be classified into catogires of a domain. For example, in the String
"Tesla is a great stock to invest in "
, the sub-string "Tesla"
is a named entity, it can be classified with the label company
by an ML algorithm.
Named entities can easily be extracted by the various pre-trained Deep Learning based NER algorithms provided by NLU.
After extracting named entities an entity resolution algorithm can be applied to the extracted named entities. The resolution algorithm classifies each extracted entitiy into a class, which reduces dimensionality of the data and has many useful applications. For example :
The sub-strings Tesla
, TSLA
and Tesla, Inc
are all named entities, that are classified with the labeld company
by the NER algorithm. It tells us, all these 3 sub-strings are of type company
, but we cannot yet infer that these 3 strings are actually referring to literally the same company.
This exact problem is solved by the resolver algorithms, it would resolve all these 3 entities to a common name, like a company ID. This maps every reference of Tesla, regardless of how the string is represented, to the same ID.
This example can analogusly be expanded to healthcare any any other text problems. In medical documents, the same disease can be referenced in many different ways.
With NLU Healthcare you can leverage state of the art pre-trained NER models to extract Medical Named Entities (Diseases, Treatments, Posology, etc..) and resolve these to common healthcare disease codes.
This algorithm is provided by Spark NLP for Healthcare's SentenceEntitiyResolver
Domain/Terminology | Description | Sample NLU Spells | Sample Entities | Sample Predicted Codes | Reference Links |
---|---|---|---|---|---|
ICD-10 / ICD-10-CM (International Classification of Diseases - Clinical Modification) | Get ICD-10-CM codes of Medical and Clinical Entities . The ICD-10 Clinical Modification (ICD-10-CM) is a modification of the ICD-10, authorized by the World Health Organization , used as a source for diagnosis codes in the U.S. Be aware, ICD10-CM is often referred to as ICD10 |
resolve.icd10cm.augmented |
hypertension , gastritis |
I10 , K2970 |
ICD-10-CM , WHO ICD-10-CM |
ICD-10-PCS (International Classification of Diseases - Procedure Coding System) | Get ICD-10-PCS codes of Medical and Clinical Entities . The International Classification of Diseases, Procedure Coding System (ICD-10-PCS) , is a U.S. cataloging system for procedural code It is maintaining by Centers for Medicare & Medicaid Services |
resolve.icd10pcs |
hypertension , gastritis |
DWY18ZZ , 04723Z6 |
ICD10-PCS, CMS ICD-10-PCS |
ICD-O (International Classification of Diseases, Oncollogy) Topography & Morphology codes | Get ICD-0 codes of Medical and Clinical Entities . The International Classification of Diseases for Oncology (ICD-O) , is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. |
resolve.icdo.base |
metastatic lung cancer |
9050/3 +C38.3 , 8001/3 +C39.8 |
ICD-O Histology Behaviour dataset |
HCC (Hierachical Conditional Categories) | Get HCC codes of Medical and Clinical Entities . Hierarchical condition category (HCC) relies on ICD-10 coding to assign risk scores to patients. Along with demographic factors (such as age and gender), insurance companies use HCC coding to assign patients a risk adjustment factor (RAF) score. |
resolve.hcc |
hypertension , gastritis |
139 , 188 |
HCC |
ICD-10-CM + HCC Billable | Get ICD-10-CM and HCC codes of Medical and Clinical Entities . |
resolve.icd10cm.augmented_billable |
metastatic lung cancer |
C7800 + ['1', '1', '8'] |
ICD10-CM HCC |
CPT (Current Procedural Terminology) | Get CPT codes of Medical and Clinical Entities . The Current Procedural Terminology(CPT) is developed by the American Medical Association (AMA) and used to assign codes to medical procedures/services/diagonstics. The codes are used to derive the amount of payment a healthcare provider may receives from insurance companies for the provided service.receives |
resolve.cpt.procedures_measurements |
calcium score , heart surgery |
82310 , 33257 |
CPT |
LOINC (Logical Observation Identifiers Names and Codes) | Get LOINC codes of Medical and Clinical Entities . Logical Observation Identifiers Names and Codes (LOINC) developed by theU.S. organization Regenstrief Institute |
resolve.loinc |
acute hepatitis ,obesity |
28083-4 ,50227-8 |
LOINC |
HPO (Human Phenotype Ontology) | Get HPO codes of Medical and Clinical Entities . |
resolve.HPO |
cancer , bipolar disorder |
0002664 , 0007302 , 0100753 |
HPO |
UMLS (Unified Medical Language System) CUI | Get UMLS codes of Medical and Clinical Entities . |
resolve.umls.findings |
vomiting , polydipsia , hepatitis |
C1963281 , C3278316 , C1963279 |
UMLS |
SNOMED International (Systematized Nomenclature of Medicine) | Get SNOMED (INT) codes of Medical and Clinical Entities . |
resolve.snomed.findings_int |
hypertension |
148439002 |
SNOMED |
SNOMED CT (Clinical Terms) | Get SNOMED (CT) codes of Medical and Clinical Entities . |
resolve.snomed.findings |
hypertension |
73578008 |
SNOMED |
SNOMED Conditions | Get SNOMED Conditions codes of Medical and Clinical Entities . |
resolve.snomed_conditions |
schizophrenia |
58214004 |
SNOMED |
RxNorm and RxCUI (Concept Uinque Indentifier) | Get Normalized RxNorm and RxCUI codes of Medical, Clinical and Drug Entities . |
resolve.rxnorm |
50 mg of eltrombopag oral |
825427 |
[RxNorm Overview] [November 2020 RxNorm Clinical Drugs ontology graph] |
# Restar Kernal and authorize again if RAM is full.
# You dont need to run this if you uploaded spark_nlp_for_healthcare.json
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
ICD-10-CM
codes of Medical and Clinical Entities
. The ICD-10 Clinical Modification (ICD-10-CM)
is a modification of the ICD-10, authorized by the World Health Organization
, used as a source for diagnosis codes in the U.S.
Be aware, ICD10-CM is often referred to as ICD10hypertension
, gastritis
I10
, K2970
import nlu
model = nlu.load('med_ner.jsl.wip.clinical resolve.icd10cm.augmented')
model.predict('Patient with history of prior tobacco use , hypertension and chronic renal insufficiency.')
model.viz('Patient with history of prior tobacco use , hypertension and chronic renal insufficiency.')
ICD-10-PCS
codes of Medical and Clinical Entities
. The International Classification of Diseases, Procedure Coding System (ICD-10-PCS)
, is a U.S.
cataloging system for procedural code It is maintaining by Centers for Medicare & Medicaid Services
removal of cast
, CT scan
2W01X2Z
, 2W61XZZ
model = nlu.load('med_ner.jsl.wip.clinical resolve.icd10pcs')
model.predict('Cast was removed from patient face. CT scan was peformed to verify findings.')
model.viz('Cast was removed from patient face. CT scan was peformed to verify findings.')
ICD-0
codes of Medical and Clinical Entities
. The International Classification of Diseases for Oncology (ICD-O)
, is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases.metastatic lung cancer
9050/3
+C38.3
, 8001/3
+C39.8
model = nlu.load('med_ner.jsl.wip.clinical resolve.icdo.base')
model.predict('mesothelioma and malignancies are developing alongside the brain tumor and breast cancer.')
model.viz('mesothelioma and malignancies are developing alongside the brain tumor and breast cancer.')
HCC
codes of Medical and Clinical Entities
. Hierarchical condition category (HCC) relies on ICD-10 coding to assign risk scores to patients. Along with demographic factors (such as age and gender), insurance companies use HCC coding to assign patients a risk adjustment factor (RAF) score.hypertension
, gastritis
139
, 188
model = nlu.load('med_ner.jsl.wip.clinical resolve.hcc')
model.predict('Patient with history of prior tobacco use , hypertension , chronic renal insufficiency , COPD and gastritis.')
model.viz('Patient with history of prior tobacco use , hypertension , chronic renal insufficiency , COPD and gastritis.')
CPT
codes of Medical and Clinical Entities
. The Current Procedural Terminology(CPT)
is developed by the American Medical Association (AMA)
and used to assign codes to medical procedures/services/diagonstics. The codes are used to derive the amount of payment a healthcare provider
may receives from insurance companies
for the provided service.receivescalcium score
, heart surgery
82310
, 33257
model = nlu.load('med_ner.jsl.wip.clinical resolve.cpt.procedures_measurements')
model.predict('Amputation on left food was performed, after heart transplant')
model.viz('Amputation on left food was performed, after heart transplant')
LOINC
codes of Medical and Clinical Entities
. LOINC is a code system for identifying test observations.acute hepatitis
,obesity
28083-4
,50227-8
model = nlu.load('med_ner.jsl.wip.clinical resolve.loinc')
model.predict('"Cancer was observed after CT scan. Blood samples confirm result')
model.viz('Cancer was observed after CT scan. Blood samples confirm result')
HPO
codes of Medical and Clinical Entities
.cancer
, bipolar disorder
0002664
, 0007302
, 0100753
model = nlu.load('med_ner.jsl.wip.clinical resolve.HPO')
model.predict("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
model.viz("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
UMLS
codes of Medical and Clinical Entities
.vomiting
, polydipsia
, hepatitis
C1963281
, C3278316
, C1963279
model = nlu.load('med_ner.jsl.wip.clinical resolve.umls.findings')
model.predict("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
model.viz("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
# Restar Kernal and authorize again if RAM is full.
# You dont need to run this if you uploaded spark_nlp_for_healthcare.json
# import nlu
# SPARK_NLP_LICENSE = '?????'
# AWS_ACCESS_KEY_ID = '?????'
# AWS_SECRET_ACCESS_KEY = '?????'
# JSL_SECRET = '?????'
# nlu.auth(SPARK_NLP_LICENSE,AWS_ACCESS_KEY_ID,AWS_SECRET_ACCESS_KEY,JSL_SECRET)
SNOMED (CT)
codes of Medical and Clinical Entities
.hypertension
73578008
import nlu
model = nlu.load('med_ner.jsl.wip.clinical resolve.snomed.findings')
model.predict('This is an 82 - year-old male with a history of prior tobacco use , hypertension , chronic renal insufficiency , COPD , gastritis , and TIA who initially presented to Braintree with a non-ST elevation MI and Guaiac positive stools , transferred to St . Margaret\'s Center for Women & Infants for cardiac catheterization with PTCA to mid LAD lesion complicated by hypotension and bradycardia requiring Atropine , IV fluids and transient dopamine possibly secondary to vagal reaction , subsequently transferred to CCU for close monitoring , hemodynamically stable at the time of admission to the CCU .')
model.viz('This is an 82 - year-old male with a history of prior tobacco use , hypertension , chronic renal insufficiency , COPD , gastritis , and TIA who initially presented to Braintree with a non-ST elevation MI and Guaiac positive stools , transferred to St . Margaret\'s Center for Women & Infants for cardiac catheterization with PTCA to mid LAD lesion complicated by hypotension and bradycardia requiring Atropine , IV fluids and transient dopamine possibly secondary to vagal reaction , subsequently transferred to CCU for close monitoring , hemodynamically stable at the time of admission to the CCU .')
SNOMED (INT)
codes of Medical and Clinical Entities
.hypertension
148439002
import nlu
model = nlu.load('med_ner.jsl.wip.clinical resolve.snomed.findings_int')
model.predict("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
model.viz("These disorders include cancer, bipolar disorder, schizophrenia, Cri-du-chat syndrome, hypermetropia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
SNOMED Conditions
codes of Medical and Clinical Entities
.schizophrenia
58214004
model = nlu.load('med_ner.jsl.wip.clinical resolve.snomed_conditions')
model.predict("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
model.viz("These disorders include cancer, bipolar disorder, schizophrenia, autism, Cri-du-chat syndrome, myopia, cortical cataract-linked Alzheimer's disease, and infectious diseases")
RxNorm
and RxCUI
codes of Medical, Clinical and Drug Entities
.50 mg of eltrombopag oral
825427
model = nlu.load('med_ner.jsl.wip.clinical resolve.rxnorm')
model.predict('He was seen by the endocrinology service and she was discharged on 50 mg of eltrombopag oral at night, 5 mg amlodipine with meals, and metformin 1000 mg two times a day')
model.viz('He was seen by the endocrinology service and she was discharged on 50 mg of eltrombopag oral at night, 5 mg amlodipine with meals, and metformin 1000 mg two times a day',viz_type='resolution')