In [1]:

```
from pathlib import Path
import numpy as np
import matplotlib.pyplot as plt
import pyhf
import pyhf.readxml
from pyhf.contrib.viz import brazil
import base64
from IPython.core.display import display, HTML
from ipywidgets import interact, fixed
```

HistFactory is a popular framework to analyze binned event data and commonly used in High Energy Physics. At its core it is a template for building a statistical model from individual binned distribution ('Histograms') and variations on them ('Systematics') that represent auxiliary measurements (for example an energy scale of the detector which affects the shape of a distribution)

`pyhf`

is a work-in-progress standalone implementation of the HistFactory p.d.f. template and an implementation of the test statistics and asymptotic formulae described in the paper by Cowan, Cranmer, Gross, Vitells: *Asymptotic formulae for likelihood-based tests of new physics* [arXiv:1007.1727].

Models can be defined using JSON specification, but existing models based on the XML + ROOT file scheme are readable as well.

The input data for the statistical analysis was built generated using the containerized workflow engine yadage (see demo from KubeCon 2018 [youtube]). Similarly to Binder this utilizes modern container technology for reproducible science. Below you see the execution graph leading up to the model input data at the bottom.

In [2]:

```
anim = base64.b64encode(open('workflow.gif', 'rb').read()).decode('ascii')
HTML(f'<img src="data:image/gif;base64,{anim}">')
```

Out[2]: